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Current Topics in Medicinal Chemistry|May 25, 2006
Optimization of small molecule drugs binding to highly polar target sites: lessons from the discovery and development of neuraminidase inhibitorsKlaus Klumpp, Bradford J GravesCurrent Topics in Medicinal Chemistry|May 25, 2006
Lessons from the drug discovery of lapatinib, a dual ErbB1/2 tyrosine kinase inhibitorKaren E LackeyCurrent Topics in Medicinal Chemistry|May 25, 2006
Biochemical mechanisms of New Molecular Entities (NMEs) approved by United States FDA during 2001-2004: mechanisms leading to optimal efficacy and safetyDavid C SwinneyCurrent Topics in Medicinal Chemistry|May 25, 2006
NMDA receptors are not alone: dynamic regulation of NMDA receptor structure and function by neuregulins and transient cholesterol-rich membrane domains leads to disease-specific nuances of glutamate-signallingAndré Schrattenholz, Vukic SoskicCurrent Topics in Medicinal Chemistry|May 25, 2006
Tricyclic quinoxalinediones, aza-kynurenic acids, and indole-2-carboxylic acids as in vivo active NMDA-glycine antagonistsRyu Nagata, Seiji Katayama, Ken-Ichi Ohtani, et al.Current Topics in Medicinal Chemistry|June 22, 2006
Co-existence of GABA and Glu transporters in the central nervous systemGiambattista Bonanno, Luca Raiteri, Silvio Paluzzi, et al.Current Topics in Medicinal Chemistry|June 22, 2006
Pharmacological roles of the large-conductance calcium-activated potassium channelSheng-Nan Wu, Adonis Z Wu, Ming-Wei LinCurrent Topics in Medicinal Chemistry|June 22, 2006
Structure-activity relationships of K(ATP) channel openersRaimund MannholdCurrent Topics in Medicinal Chemistry|June 22, 2006
From cromakalim to different structural classes of K(ATP) channel openersVioletta Cecchetti, Oriana Tabarrini, Stefano SabatiniCurrent Topics in Medicinal Chemistry|July 14, 2007
An update in the development of HIV entry inhibitorsStefano Rusconi, Andrea Scozzafava, Antonio Mastrolorenzo, et al.Pageof 421