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Disease Models & Mechanisms|July 22, 2024
Human organoid model of pontocerebellar hypoplasia 2a recapitulates brain region-specific size differencesTheresa Kagermeier, Stefan Hauser, Kseniia Sarieva, et al.
Disease Models & Mechanisms|August 27, 2024
A deleterious variant of INTS1 leads to disrupted sleep-wake cyclesShir Confino, Yair Wexler, Adar Medvetzky, et al.
Disease Models & Mechanisms|August 27, 2024
Reduced connexin-43 expression, slow conduction and repolarisation dispersion in a model of hypertrophic cardiomyopathySeakcheng Lim, Melissa M Mangala, Mira Holliday, et al.
Disease Models & Mechanisms|May 28, 2024
Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disordersElisa M Crombie, Andrea J Korecki, Karen Cleverley, et al.
Disease Models & Mechanisms|June 17, 2024
Computational identification of disease models through cross-species phenotype comparisonPilar Cacheiro, Diego Pava, Helen Parkinson, et al.
Disease Models & Mechanisms|July 8, 2024
CCL2 signaling promotes skeletal muscle wasting in non-tumor and breast tumor modelsNadia Alissa, Wei Bin Fang, Marcela Medrano, et al.
Disease Models & Mechanisms|May 17, 2024
Female Alms1-deficient mice develop echocardiographic features of adult but not infantile Alström syndrome cardiomyopathyEleanor J McKay, Ineke Luijten, Sophie Broadway-Stringer, et al.
Disease Models & Mechanisms|August 16, 2023
CRISPR-based knockout and base editing confirm the role of MYRF in heart development and congenital heart diseaseLino Doering, Alex Cornean, Thomas Thumberger, et al.
Disease Models & Mechanisms|October 10, 2023
Altered binding affinity of SIX1-Q177R correlates with enhanced WNT5A and WNT pathway effector expression in Wilms tumorMatthew J Stevenson, Sabrina K Phanor, Urvi Patel, et al.
Disease Models & Mechanisms|October 4, 2023
Transcriptomic analysis of diabetic kidney disease and neuropathy in mouse models of type 1 and type 2 diabetesSarah E Elzinga, Stephanie A Eid, Brett A McGregor, et al.
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