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Disease Models & Mechanisms|August 19, 2025
Loss of Drosophila ribosomal protein S6 kinase II causes mitochondrial dysfunction and cell deathTing Deng, Lajos Kalmar, Samantha Loh, et al.
Disease Models & Mechanisms|November 14, 2022
17q12 deletion syndrome mouse model shows defects in craniofacial, brain and kidney development, and glucose homeostasisEmily B Warren, Juan A Briano, Jacob Ellegood, et al.
Disease Models & Mechanisms|November 14, 2022
Ts66Yah, a mouse model of Down syndrome with improved construct and face validityArnaud Duchon, Maria Del Mar Muñiz Moreno, Claire Chevalier, et al.
Disease Models & Mechanisms|February 10, 2026
Multi-omic analyses identify molecular targets of Chd7 that contribute to CHARGE syndrome model phenotypesMelody B Hancock, Dana R Ruby, Rachael A Bieler, et al.
Disease Models & Mechanisms|January 30, 2026
Generating cerebellar organoids from pluripotent stem cellsEsther B E Becker, Simone Mayer, Lena M Kutscher
Disease Models & Mechanisms|July 31, 2025
Evidence of neuronal DNA damage in the brains of patients with Rett syndromeAbril Morales, Elena Korsakova, Niloufar Mansooralavi, et al.
Disease Models & Mechanisms|August 1, 2025
HIV-1 Nef synergizes with APOL1-G1 to induce nephrocyte cell death in HIV-related kidney diseasesJun-Yi Zhu, Yulong Fu, Joyce van de Leemput, et al.
Disease Models & Mechanisms|August 1, 2025
Understanding Duchenne muscular dystrophy-associated brain pathologyMinou A T Verhaeg, Rosanne Govaarts, Maaike van Putten
Disease Models & Mechanisms|June 20, 2025
Mutant zebrafish lacking slc25a22a show spontaneous seizures and respond to the anti-seizure medication valproic acidSo-Hyun Lee, Ting Liang, Gopalakrishnan Chandrasekaran, et al.
Disease Models & Mechanisms|April 8, 2025
Translating animal models of SARS-CoV-2 infection to vascular, neurological and gastrointestinal manifestations of COVID-19James Chung, Julia Pierce, Craig Franklin, et al.
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