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Drug Design, Development and Therapy|April 17, 2026
Single-Cell Transcriptomics Reveals Riluzole as an Osteoarthritis Candidate Drug via OB-NE Signaling Modulation and CTSS/NOS1 InhibitionKun Liu, Jia-Li Li, Yan Chen, et al.
Drug Design, Development and Therapy|April 27, 2026
Defining the Therapeutic Range of Levetiracetam for Personalized Treatment in Pediatric Epilepsy: Insights from a Large Real-World StudyXi-Li Sun, Yuan-Yuan Zhang, Yi-Jing Liu, et al.
Drug Design, Development and Therapy|March 20, 2026
Effects of Cipepofol on Cardiac Depolarization and Repolarization in Healthy Subjects: A Single-Center, Randomized, Placebo and Positive-Controlled Thorough QT StudyRobert Kleiman, Todd Rudo, William Daley, et al.
Drug Design, Development and Therapy|March 20, 2026
Population Pharmacokinetics and Dosing Regimen Optimization of Piperacillin in Critically Ill PatientsZhonghua Dong, Haiyan Shi, Yilei Yang, et al.
Drug Design, Development and Therapy|March 26, 2026
ED95 of Liposomal Bupivacaine for Postoperative Local Infiltration Analgesia in Women Undergoing Cesarean Section: A Randomized Controlled TrialJiafei Liu, Yang Zhang, Lin Liu, et al.
Drug Design, Development and Therapy|March 26, 2026
A Multi-Center Study of Population Pharmacokinetics of Polymyxin B in Critically Ill PatientsYirong Wang, Xipei Wang, Liming Lei, et al.
Drug Design, Development and Therapy|March 26, 2026
Efficacy and Safety of Different Colistin Administration Routes for Nosocomial Pneumonia Caused by Carbapenem-Resistant Organisms: A Single Centre, Open Label, Prospective Cohort StudyQiao-Yi Wei, Wei Shen, Zhao-Yuan Chen, et al.
Drug Design, Development and Therapy|March 26, 2026
Comparative Effectiveness of Single-Dose Epidural Esketamine versus Hydromorphone in Thoracic and Upper Abdominal Surgery: A Randomized TrialYuejiao Song, Chengyu Wang, Ning Huang, et al.
Drug Design, Development and Therapy|March 25, 2026
One-Day Aminoglycosides versus Three-Day Ceftazidime for Perioperative Prophylaxis and Postoperative Sepsis Risk in Patients with Urinary Calculi: A Propensity Score-Matched Retrospective Cohort AnalysisShuangshuang Sun, Jinlin Guo, Zhijia Zhang, et al.
Drug Design, Development and Therapy|March 25, 2026
Efficacy and Safety of Finerenone Combined with Dapagliflozin in the Treatment of Non-Diabetic Chronic Kidney Disease: A Single-Center Retrospective StudyJianwei Ma, Qin Su, Hanlu Wang, et al.
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