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Drug Design, Development and Therapy|September 9, 2015
A bioinformatic and mechanistic study elicits the antifibrotic effect of ursolic acid through the attenuation of oxidative stress with the involvement of ERK, PI3K/Akt, and p38 MAPK signaling pathways in human hepatic stellate cells and rat liverWenhua He, Feng Shi, Zhi-Wei Zhou, et al.Drug Design, Development and Therapy|September 11, 2015
CXCR4 in breast cancer: oncogenic role and therapeutic targetingChao Xu, Hong Zhao, Haitao Chen, et al.Drug Design, Development and Therapy|February 3, 2016
YiQiFuMai powder injection ameliorates blood-brain barrier dysfunction and brain edema after focal cerebral ischemia-reperfusion injury in miceGuosheng Cao, Xinyi Ye, Yingqiong Xu, et al.Drug Design, Development and Therapy|January 15, 2016
Effect of milrinone on cardiac functions in patients undergoing coronary artery bypass graft: a meta-analysis of randomized clinical trialsZhigang You, Lin Huang, Xiaoshu Cheng, et al.Drug Design, Development and Therapy|January 15, 2016
MicroRNA-125a-5p modulates human cervical carcinoma proliferation and migration by targeting ABL2Xian Qin, Yajun Wan, Saiying Wang, et al.Drug Design, Development and Therapy|January 15, 2016
The gastroprotective effects of hydroalcoholic extract of Monolluma quadrangula against ethanol-induced gastric mucosal injuries in Sprague Dawley ratsIbrahim Abdel Aziz Ibrahim, Mahmood Ameen Abdulla, Maryam Hajrezaie, et al.Drug Design, Development and Therapy|December 18, 2015
Identification of covalent active site inhibitors of dengue virus proteaseXiaoying Koh-Stenta, Joma Joy, Si Fang Wang, et al.Drug Design, Development and Therapy|January 22, 2016
Design, synthesis, and antihypertensive activity of curcumin-inspired compounds via ACE inhibition and vasodilation, along with a bioavailability study for possible benefit in cardiovascular diseasesXiao-Dong Zhuang, Li-Zhen Liao, Xiao-Bian Dong, et al.Drug Design, Development and Therapy|January 22, 2016
Discovery of a novel anticancer agent with both anti-topoisomerase I and II activities in hepatocellular carcinoma SK-Hep-1 cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehydeDaw-Shyong Perng, Yu-Hsin Tsai, Jonathan Cherng, et al.Drug Design, Development and Therapy|December 31, 2015
Idiopathic pulmonary fibrosis: current treatment options and critical appraisal of nintedanibFrancesco Bonella, Susanne Stowasser, Lutz WollinPageof 584