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Drug Development Research|April 7, 2025
HIF-Prolyl Hydroxylase Inhibitor Desidustat Increases Pyruvate Kinase Activity and Reduces Oxidative Stress in Red Blood Cells, Causes Erythrocytosis in Thalassaemic Mice, and Reduces Sickling in Sickle Cell Patient's BloodVishal J Patel, Amit A Joharapurkar, Samadhan G Kshirsagar, et al.
Drug Development Research|May 19, 2025
Repurposing Nitroimidazoles: A New Frontier in Combatting Bacterial Virulence and Quorum Sensing via In Silico, In Vitro, and In Vivo InsightsEl-Sayed Khafagy, Ahmed Al Saqr, Bjad K Almutairy, et al.
Drug Development Research|May 9, 2025
Tannic Acid as an Ion Channel Modulator: An Understanding of Its Pharmacological SpectrumKing-Chuen Wu, Chiu-Yin Lee, Paul Chan, et al.
Drug Development Research|March 28, 2025
Novel 3-Substituted-2H-Chromene Scaffold Based Fluorinated Hydrophobic Fragment as In-Vitro Antiproliferative Agents and Apoptosis Inducers Targeting Both VEGFR-2/BRAFV600E and h-DHFR With Molecular Docking SimulationMohamed A Salem, Moustafa S Abusaif, Nirvana A Gohar, et al.
Drug Development Research|December 4, 2025
Synthesis and Biological Evaluation of π-Conjugated Ir(III) Complexes: Cytotoxic Potential, DNA/HSA Binding, Thermodynamics, and Antioxidant ActivityBhumika Joshi, Priyankar Paira, Kaliappan Uma, et al.
Drug Development Research|September 24, 2025
Nanoparticle-Integrated Transdermal Patches: A Platform for Next-Generation Drug DeliveryNeethi Mohan, Remya Prabhavathi Amma Neelakandan Nair, Damodharan Narayanasamy
Drug Development Research|August 14, 2025
Ethyl Linoleate Ameliorates Synovial Cell Proliferation and Inflammatory Cell Infiltration in Rheumatoid Arthritis Through DKK1/Wnt-OPG Signal Axis and AutophagyZong Jiang, XiaoLing Yao, Xin Cai, et al.
Drug Development Research|August 8, 2025
Investigating the Effects of Curcumin on Lipid Metabolism and Cell Viability in HepG2 Cells: Potential Therapeutic Implications for Nonalcoholic Fatty Liver DiseaseFaeze Qaleban, Javad Mohammadnejad, Amin Daemi, et al.
Drug Development Research|September 8, 2025
Lazertinib: A Cardio-Safer Alternative to Osimertinib for Epidermal Growth Factor Receptor L858R/T790M Double-Mutant Tyrosine Kinase Resistant Non-Small Cell Lung CancerChandrakant S Gawli, Narendra R Nagpure, Bhatu R Patil, et al.
Drug Development Research|September 23, 2025
Exploring Novel Tetrahydropyrimidine and Fused Pyrimidine-Based Compounds as DHFR Inhibitors and Antimicrobial Agents: Synthesis, In Vitro, In Vivo, and In Silico StudiesMenna M Sherif, Basem Mansour, May A El-Antrawy, et al.
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