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European Journal of Medicinal Chemistry|August 20, 2022
Design, synthesis, and biological evaluation of novel dual inhibitors of heat shock protein 90/mammalian target of rapamycin (Hsp90/mTOR) against bladder cancer cellsZhaoping Pan, Yi Chen, Haiying Pang, et al.
European Journal of Medicinal Chemistry|May 13, 2021
Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives to reduce SREBPs expression for the treatment of hyperlipidemiaHaixia Ge, Weitao Zhang, Kai Yuan, et al.
European Journal of Medicinal Chemistry|May 15, 2021
Polymyxin B-inspired non-hemolytic tyrocidine A analogues with significantly enhanced activity against gram-negative bacteria: How cationicity impacts cell specificity and antibacterial mechanismJibao Zhu, Chengfei Hu, Zizhen Zeng, et al.
European Journal of Medicinal Chemistry|May 16, 2021
PdCl2-catalyzed synthesis of a new class of isocoumarin derivatives containing aminosulfonyl / aminocarboxamide moiety: First identification of a isocoumarin based PDE4 inhibitorB Thirupataiah, Guntipally Mounika, Gangireddy Sujeevan Reddy, et al.
European Journal of Medicinal Chemistry|May 17, 2021
Isoxazole derivatives as anticancer agent: A review on synthetic strategies, mechanism of action and SAR studiesGirish Chandra Arya, Kamalpreet Kaur, Vikas Jaitak
European Journal of Medicinal Chemistry|May 18, 2021
Chemical modification of NSC12 leads to a specific FGF-trap with antitumor activity in multiple myelomaRiccardo Castelli, Sara Taranto, Lucia Furiassi, et al.
European Journal of Medicinal Chemistry|August 8, 2022
Design, synthesis, and biological evaluation of pyrrolopyrimidine derivatives as novel Bruton's tyrosine kinase (BTK) inhibitorsMinjian Yang, Huimin Jiang, Zhuo Yang, et al.
European Journal of Medicinal Chemistry|August 8, 2022
Design, synthesis and antitumor evaluation of ATP dual-mimic 2,4-diarylaminopyrimidine and aminoindazole conjugates as potent anaplastic lymphoma kinase inhibitorsJing Yang, Deyi Ma, Shuyu Liu, et al.
European Journal of Medicinal Chemistry|August 6, 2022
An auristatin-based peptide-drug conjugate targeting Kita-Kyushu lung cancer antigen 1 for precision chemoradiotherapy in gastric cancerXiaotong Chen, Fangcen Liu, Xiaoxiao Yu, et al.
European Journal of Medicinal Chemistry|August 6, 2022
Novel analgesic/anti-inflammatory agents: 1,5-Diarylpyrrole nitrooxyethyl sulfides and related compounds as Cyclooxygenase-2 inhibitors containing a nitric oxide donor moiety endowed with vasorelaxant propertiesMario Saletti, Samuele Maramai, Annalisa Reale, et al.
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