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European Journal of Medicinal Chemistry|September 18, 2021
Discovery of highly potent human glutaminyl cyclase (QC) inhibitors as anti-Alzheimer's agents by the combination of pharmacophore-based and structure-based designNguyen Van Manh, Van-Hai Hoang, Van T H Ngo, et al.
European Journal of Medicinal Chemistry|September 18, 2021
A novel methylenemalononitrile-BODIPY-based fluorescent probe for highly selective detection of hydrogen peroxide in living cellsYong-Feng Wei, Xuan Wang, Wen-Jing Shi, et al.
European Journal of Medicinal Chemistry|August 16, 2021
Study on the structure-activity relationship of dihydroartemisinin derivatives: Discovery, synthesis, and biological evaluation of dihydroartemisinin-bile acid conjugates as potential anticancer agentsXiaosu Zou, Chang Liu, Congcong Li, et al.
European Journal of Medicinal Chemistry|August 17, 2021
Design, synthesis, and SAR study of novel 4,5-dihydropyrazole-Thiazole derivatives with anti-inflammatory activities for the treatment of sepsisZhen Zhang, Peichang Cao, Mengyuan Fang, et al.
European Journal of Medicinal Chemistry|August 17, 2021
Evaluating the mechanisms of action and subcellular localization of ruthenium(II)-based photosensitizersJiancheng Mo, Ngoc Phuong Mai Le, Ronny Priefer
European Journal of Medicinal Chemistry|August 21, 2021
From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effectsCaterina Pont, Tiziana Ginex, Christian Griñán-Ferré, et al.
European Journal of Medicinal Chemistry|August 15, 2021
Synthesis, structure-activity relationships, cocrystallization and cellular characterization of novel smHDAC8 inhibitors for the treatment of schistosomiasisEhab Ghazy, Tino Heimburg, Julien Lancelot, et al.
European Journal of Medicinal Chemistry|April 26, 2020
Substituted oxindol-3-ylidenes as AMP-activated protein kinase (AMPK) inhibitorsChristopher J Matheson, Kimberly A Casalvieri, Donald S Backos, et al.
European Journal of Medicinal Chemistry|May 14, 2020
Discovery of potent and highly selective covalent inhibitors of Bruton's tyrosine kinase bearing triazine scaffoldYu Teng, Xiang Lu, Maoxu Xiao, et al.
European Journal of Medicinal Chemistry|May 8, 2020
N-alkylpiperidine carbamates as potential anti-Alzheimer's agentsUrban Košak, Nika Strašek, Damijan Knez, et al.
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