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European Journal of Medicinal Chemistry|February 1, 2025
Identification of Thieno[3,2-d]pyrimidine derivatives as potent and selective Janus Kinase 1 inhibitorsYounghoon Kim, Eunhye Jeon, Hyunwoo Ahn, et al.
European Journal of Medicinal Chemistry|January 30, 2025
The chiral 5,6-cyclohexane-fused uracil ring-system: A molecular platform with promising activity against SARS-CoV-2Enrico Marcantonio, Debora Guazzetti, Crescenzo Coppa, et al.
European Journal of Medicinal Chemistry|January 31, 2025
Discovery of the first potent ROR1 degrader for the treatment of non-small cell lung cancerJinlin Li, Lin Li, Caiyun Hou, et al.
European Journal of Medicinal Chemistry|January 16, 2025
Discovery of CZY43 as a new small-molecule degrader of pseudokinase HER3Zhiyuan Chen, Rui He, Shengjie Huang, et al.
European Journal of Medicinal Chemistry|January 20, 2025
Discovery of noncovalent diaminopyrimidine-based Inhibitors for glioblastoma via a dual FAK/DNA targeting strategyYi Wei, Xiaoling He, Zhiwu Long, et al.
European Journal of Medicinal Chemistry|January 18, 2025
A novel pyridine-2-one AMPK inhibitor: Discovery, mechanism, and in vivo evaluation in a hypoxic pulmonary arterial hypertension rat modelWenhua Tan, Yu Wang, Mengqi Li, et al.
European Journal of Medicinal Chemistry|January 22, 2025
Discovery of novel fluorine-containing parthenolide analogues as potential antitumor agentsXiyan Duan, Junqi Wang, Xiaoguang Huo, et al.
European Journal of Medicinal Chemistry|January 9, 2025
Overview of the epigenetic/cytotoxic dual-target inhibitors for cancer therapyHailiu Liang, Shuqing Li, Xiaopeng Peng, et al.
European Journal of Medicinal Chemistry|January 10, 2025
Discovery of new inhibitors of nuclease MRE11Fedor Nikulenkov, Benoit Carbain, Raktim Biswas, et al.
European Journal of Medicinal Chemistry|January 12, 2025
Progress in the study of anti-Alzheimer's disease activity of pyrimidine-containing bioactive moleculesYu-Lin Liu, Qian Zhang, Bing-Qian Li, et al.
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