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European Journal of Medicinal Chemistry|November 22, 2024
Discovery of a highly potent, N-terminal domain-targeting degrader of AR-FL/AR-V7 for the treatment of prostate cancerSi Ha, Chenxuan Ji, Jiaqi Yang, et al.
European Journal of Medicinal Chemistry|November 21, 2024
Optimization of SHP2 allosteric inhibitors with novel tail heterocycles and their potential as antitumor therapeuticsChengchun Zhu, Leilei Li, Yan Yu, et al.
European Journal of Medicinal Chemistry|November 12, 2024
Discovery of 4-(4-(3-(1-(2-(piperidin-1-yl)ethyl)-1H-benzo[d]imidazole-2-yl)isoxazol-5-yl)phenyl)morpholine as a novel c-Myc inhibitor against lung cancer in vitro and in vivoJian Gao, Jiacheng Yin, Shihao Li, et al.
European Journal of Medicinal Chemistry|November 11, 2024
Design, synthesis, and cytotoxicity screening of novel pyrazolopyrimidines over renal cell carcinoma (UO-31 cells) as p38α inhibitors, and apoptotic cells inducing activitiesSara Y Ewieda, Amr Sonousi, Aliaa M Kamal, et al.
European Journal of Medicinal Chemistry|November 8, 2024
Discovery of pyrrolopyrimidinone derivatives as potent PKMYT1 inhibitors for the treatment of cancerChao Wang, Yazhou Wang, Fanye Meng, et al.
European Journal of Medicinal Chemistry|February 14, 2025
Spirocyclic compounds as innovative tools in drug discovery for medicinal chemistsMarina T Varela, Gleiston G Dias, Luiz Fernando N de Oliveira, et al.
European Journal of Medicinal Chemistry|February 23, 2025
Exploring β-carboline hybrids and their derivatives: A review on synthesis and anticancer efficiencyNur Fatihah Sulaiman, Siti Zafirah Zulkifli, Aimi Suhaily Saaidin, et al.
European Journal of Medicinal Chemistry|February 25, 2025
Multifunctional metal-organic frameworks in breast cancer therapy: Advanced nanovehicles for effective treatmentShefali Shukla, Dipankar Bagchi, Divya, et al.
European Journal of Medicinal Chemistry|February 24, 2025
Recent advances in metal-based nanomaterials for malignant bone tumor therapyWeicong Liu, Manli Guo, Yuanyuan Hu, et al.
European Journal of Medicinal Chemistry|February 28, 2025
Design, synthesis and optimization of Apcin analogues as Cdc20 inhibitors for triple-negative breast cancer therapyXiangyang Le, Qingsong Chen, Qiwan Wen, et al.
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