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European Journal of Medicinal Chemistry|February 13, 2025
Discovery of 2,4-diaminopyrimidine derivatives as potent inhibitors of FAK capable of activating the Hippo pathway for the treatment of esophageal squamous cell carcinomaXiao Wang, Yin-Ru Li, Ji Wu, et al.
European Journal of Medicinal Chemistry|February 13, 2025
Highlights on U.S. FDA-approved halogen-containing drugs in 2024Saghir Ali, Xiaochen Tian, Salvatore A Meccia, et al.
European Journal of Medicinal Chemistry|February 19, 2025
Identification of constrained peptidomimetics carrying a Michael acceptor warhead as antitrypanosomal agentsSanto Previti, Elsa Calcaterra, Carla Di Chio, et al.
European Journal of Medicinal Chemistry|February 20, 2025
Discovery of a first-in-class PROTAC degrader of histone lysine demethylase KDM4Danni Rao, Yiting Wang, Xiaolong Yang, et al.
European Journal of Medicinal Chemistry|November 7, 2024
Understanding the synergistic sensitization of natural products and antibiotics: An effective strategy to combat MRSASisi Chen, Ziling Zhi, Wing-Leung Wong, et al.
European Journal of Medicinal Chemistry|November 4, 2024
Design, synthesis and biological evaluation of N-benzylaryl cinnamide derivatives as tubulin polymerization inhibitors capable of promoting YAP degradation with potent anti-gastric cancer activitiesXiang-Jing Fu, Jiao Huang, Na Li, et al.
European Journal of Medicinal Chemistry|October 29, 2024
Design, synthesis, and pharmacological characterization of sulfonylurea-based NLRP3 inhibitors: Towards an effective therapeutic strategy for Alzheimer's diseaseWeiping Lyu, Tongfei Gao, Cheng Shi, et al.
European Journal of Medicinal Chemistry|October 31, 2024
Natural phenol carbamates: Selective BuChE/FAAH dual inhibitors show neuroprotection in an Alzheimer's disease mouse modelKuanrong Rong, Ziyun Li, Xiaoming Wu, et al.
European Journal of Medicinal Chemistry|November 3, 2024
One stone two birds: Introducing piperazine into a series of nucleoside derivatives as potent and selective PRMT5 inhibitorsHuaxuan Li, Hong Yang, Li Liu, et al.
European Journal of Medicinal Chemistry|November 2, 2024
Adeno-associated viral vectors deliver gene vaccinesLai Wei, Peng Yu, Haomeng Wang, et al.
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