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European Journal of Medicinal Chemistry|November 6, 2025
Discovery of highly selective and potent HPK1 inhibitors for cancer immunotherapyWei Huang, Xiao-E Yan, Jingwen Wang, et al.
European Journal of Medicinal Chemistry|November 4, 2025
Development of a series of novel potent and selective irreversible covalent FGFR4 inhibitors with a mix-and-match strategyJiajun Huang, Zhenpeng Zhong, Zhengying Pan
European Journal of Medicinal Chemistry|November 5, 2025
Radiosynthesis and PET evaluation of [18F]Fuzuloparib as a PARP-targeted imaging agent in breast cancerWei Xu, Junjie Yan, Donghui Pan, et al.
European Journal of Medicinal Chemistry|November 5, 2025
Coixol derivatives induce DNA damage by targeting PARP1Yiwei Zheng, Yuhan Jiang, Long Zheng, et al.
European Journal of Medicinal Chemistry|November 2, 2025
Discovery of selective PARP1/EZH2 inhibitor inducing PANoptosis in triple-negative breast cancerHeqing Fan, Fangbo Deng, Yiling Lai, et al.
European Journal of Medicinal Chemistry|November 18, 2025
Identification of EEF1A2 as a potential therapy target of osteosarcoma using novel compound 8eJian Xue, Meng Li, Ying Wang, et al.
European Journal of Medicinal Chemistry|October 31, 2025
Design and synthesis of Entadamide A derivatives targeting breast cancer: Insights into In silico, In vitro and In vivo modelsSathi Bhulakshmi, Nidhi Sharma, Nikhila Yaladanda, et al.
European Journal of Medicinal Chemistry|October 31, 2025
α6 nicotinic acetylcholine receptors: A pharmacological challenge with untapped therapeutic promiseBaojian Zhang, Kailin Mao, Linlin Ma, et al.
European Journal of Medicinal Chemistry|October 31, 2025
Design, synthesis, and induction of tumor ferroptosis activity of a novel FSP1 protein degrading agentYanhong Huang, Qiao Liu, Jinzhuo Li, et al.
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