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European Journal of Medicinal Chemistry|October 8, 2025
Novel PROTACs targeting tissue transglutaminase (TG2) suppress tumorigenicity of ovarian cancer cellsAndres Valdivia, Joshua L Zhu, Vanessa Hernandez, et al.
European Journal of Medicinal Chemistry|October 8, 2025
Lipophilic integrated bioorthogonal self-catalyzed nitric oxide donor-platinum(IV) prodrugs for enhanced antitumor efficacy against esophageal cancerZiyu Qian, Xun Yuan, Qing Zhao, et al.
European Journal of Medicinal Chemistry|October 7, 2025
Recent advances and strategies in BET bromodomain inhibition for drug discoveryPing-Fan Zhang, Yi-Sheng Li, Cheng Wang, et al.
European Journal of Medicinal Chemistry|October 9, 2025
Synthesis, SAR, and biophysical mechanism of action of cyclopropabenzindole-pyridinobenzodiazepine (CBI-PDD) guanine-adenine DNA cross-linking agentsGeorge Procopiou, Paul J M Jackson, Daniella di Mascio, et al.
European Journal of Medicinal Chemistry|October 15, 2025
Harnessing benzofuran scaffolds: A journey through design, synthesis, and biological discovery toward safer anti-diabetic and anti-oxidant candidatesMohamed K Elgohary, Mahmoud S Elkotamy, Mariam M Fakhry, et al.
European Journal of Medicinal Chemistry|October 15, 2025
MraY: An emerging therapeutic target in bacterial peptidoglycan biosynthesis for the discovery of novel antibiotics from natural and synthetic originSwagatika Dash, Amit Sharma, Suvarna G Kini
European Journal of Medicinal Chemistry|October 14, 2025
Extending the chemical space of glutarimide-based cereblon ligands through an efficient Rh(II)-catalyzed X-H insertion reactionEkaterina Levashova, Luca Bischof, Alexander Bunev, et al.
European Journal of Medicinal Chemistry|October 14, 2025
Targeting drug-resistant E. coli with quinoline-thiazolidinone derivatives: A new avenue for combating antibacterial resistance from molecular design to mechanistic actionPalak Sharma, Kamaldeep Paul
European Journal of Medicinal Chemistry|October 11, 2025
Mighty mini-PROTACs: an emerging class of degradersXiao Chen, Kefan Liao, Jiawei Yuan, et al.
European Journal of Medicinal Chemistry|October 11, 2025
BRITE-338733: From RecA inhibition to cancer treatmentTiyyaba Furqan, Amira Bekdash, Jisha Chalissery, et al.
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