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European Journal of Medicinal Chemistry|January 22, 2022
Structure-based design, synthesis and biological evaluation of aminopyrazines as highly potent, selective, and cellularly active allosteric SHP2 inhibitorsKai Tang, Min Zhao, Ya-Hong Wu, et al.
European Journal of Medicinal Chemistry|January 22, 2022
Overview of the development of selective androgen receptor modulators (SARMs) as pharmacological treatment for osteoporosis (1998-2021)Youquan Xie, Yucheng Tian, Yuming Zhang, et al.
European Journal of Medicinal Chemistry|February 1, 2022
Drug discovery of histone lysine demethylases (KDMs) inhibitors (progress from 2018 to present)Xingrui He, Hang Zhang, Yingqian Zhang, et al.
European Journal of Medicinal Chemistry|February 1, 2022
Synthesis, biological evaluation, and molecular modeling simulations of new heterocyclic hybrids as multi-targeted anti-Alzheimer's agentsOmnia M Waly, Kareem M Saad, Hussein I El-Subbagh, et al.
European Journal of Medicinal Chemistry|April 16, 2022
Non-peptidyl non-covalent cathepsin C inhibitoEEr bearing a unique thiophene-substituted pyridine: Design, structure-activity relationship and anti-inflammatory activity in vivoXing Chen, Yaoyao Yan, Juncheng Du, et al.
European Journal of Medicinal Chemistry|April 16, 2022
Pyrazolones as inhibitors of immune checkpoint blocking the PD-1/PD-L1 interactionRaphaël Le Biannic, Romain Magnez, Frédérique Klupsch, et al.
European Journal of Medicinal Chemistry|April 17, 2022
Selective degradation of PARP2 by PROTACs via recruiting DCAF16 for triple-negative breast cancerChunlan Pu, Yu Tong, Yuanyuan Liu, et al.
European Journal of Medicinal Chemistry|April 18, 2022
Design, synthesis and promising anti-tumor efficacy of novel imidazo[1,2-a]pyridine derivatives as potent autotaxin allosteric inhibitorsHongrui Lei, Xinyu Wang, Guolong Zhao, et al.
European Journal of Medicinal Chemistry|July 14, 2022
Design, synthesis, and biological evalution of bifunctional inhibitors against Hsp90-HDAC6 interplayHye Yun Chae, Sun You Park, Sonam Jha, et al.
European Journal of Medicinal Chemistry|July 15, 2022
A systematic exploration of boceprevir-based main protease inhibitors as SARS-CoV-2 antiviralsYugendar R Alugubelli, Zhi Zachary Geng, Kai S Yang, et al.
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