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European Journal of Medicinal Chemistry|November 28, 2023
Development of a new class of potent and highly selective G protein-coupled receptor kinase 5 inhibitors and structural insight from crystal structures of inhibitor complexesYueyi Chen, Amol Sonawane, Rajesh Manda, et al.
European Journal of Medicinal Chemistry|November 22, 2023
Discovery of C-3 isoxazole substituted thiochromone S,S-dioxide derivatives as potent and selective inhibitors for monoamine oxidase B (MAO-B)Pengbing Mi, Yan Tan, Shiying Ye, et al.
European Journal of Medicinal Chemistry|November 23, 2023
Novel ligustilide derivatives target quorum sensing system LasR/LasB and relieve inflammatory response against Pseudomonas aeruginosa infectionJun Liu, Qiu-Xian Chen, Wen-Fu Wu, et al.
European Journal of Medicinal Chemistry|November 21, 2023
HDAC specificity and kinase off-targeting by purine-benzohydroxamate anti-hematological tumor agentsKaroline B Waitman, Larissa C de Almeida, Marina C Primi, et al.
European Journal of Medicinal Chemistry|November 4, 2023
From garden to lab: C-3 chemical modifications of tomatidine unveil broad-spectrum ATP synthase inhibitors to combat bacterial resistanceJulien A Delbrouck, Alexandre Murza, Iryna Diachenko, et al.
European Journal of Medicinal Chemistry|November 3, 2023
Synthetic approaches and application of clinically approved small-molecule drugs to treat hepatitisZhen-Xi Niu, Peng Nie, Piet Herdewijn, et al.
European Journal of Medicinal Chemistry|November 17, 2023
Development of a specific and potent IGF2BP1 inhibitor: A promising therapeutic agent for IGF2BP1-expressing cancersAmandeep Singh, Vikash Singh, Nadav Wallis, et al.
European Journal of Medicinal Chemistry|November 16, 2023
Discovery of 4-(N-dithiobenzyl piperazine)-1,8-naphthalimide as a potent multi-target antitumor agent with good efficacy, limited toxicity, and low resistanceSi-Min Liang, Gui-Bin Liang, Hui-Ling Wang, et al.
European Journal of Medicinal Chemistry|November 10, 2023
Discovery of benzamide-based PI3K/HDAC dual inhibitors with marked pro-apoptosis activity in lymphoma cellsJingjing Deng, Baogeng Hou, Xiaohan Hou, et al.
European Journal of Medicinal Chemistry|November 17, 2023
Synthesis of cinnamoyl tethered indoline derivatives with anti-inflammatory and antioxidant activitiesYongpeng Liu, Jing Sun, Yichuan Ran, et al.
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