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European Journal of Medicinal Chemistry|July 23, 2023
A facile and selective derivatization approach on kynurenine-NH2 in daptomycin, leading to the discovery of hexakynomycin to combat multidrug-resistant Gram-positive pathogens especially daptomycin-resistant bacteriaDongliang Guan, Jian Li, Feifei Chen, et al.
European Journal of Medicinal Chemistry|July 23, 2023
Metabolism-guided development of Ko143 analogs as ABCG2 inhibitorsJunjie Zhu, Saifei Lei, Jie Lu, et al.
European Journal of Medicinal Chemistry|July 21, 2023
Exploring the 1,3-benzoxazine chemotype for cannabinoid receptor 2 as a promising anti-cancer therapeuticNicola Gambacorta, Valeria Gasperi, Tatiana Guzzo, et al.
European Journal of Medicinal Chemistry|July 24, 2023
Discovery of Ibrutinib-based BTK PROTACs with in vivo anti-inflammatory efficacy by inhibiting NF-κB activationJunli Huang, Zeli Ma, Zichao Yang, et al.
European Journal of Medicinal Chemistry|July 8, 2023
The role of natural anti-parasitic guided development of synthetic drugs for leishmaniasisRohit Pal, Ghanshyam Teli, Md Jawaid Akhtar, et al.
European Journal of Medicinal Chemistry|July 8, 2023
Design, synthesis, and biological evaluation of a series of new anthraquinone derivatives as anti-ZIKV agentsYujia Zhu, Jianchen Yu, Tao Chen, et al.
European Journal of Medicinal Chemistry|July 10, 2023
Are inhibitors of histone deacetylase 8 (HDAC8) effective in hematological cancers especially acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL)?Sk Abdul Amin, Samima Khatun, Shovanlal Gayen, et al.
European Journal of Medicinal Chemistry|July 6, 2023
Recent advances of targeting nicotinamide phosphoribosyltransferase (NAMPT) for cancer drug discoveryHe Tang, Lin Wang, Tianyu Wang, et al.
European Journal of Medicinal Chemistry|June 29, 2023
Design, synthesis, and biological evaluation of novel spirocyclic compounds as potential anti-glioblastoma agentsHeping Zhu, Xiaomin Song, Yihui Pan, et al.
European Journal of Medicinal Chemistry|July 6, 2023
Design, synthesis, and biological studies of novel sulfonamide derivatives as farnesoid X receptor agonistsWenxin Wang, Zhijun Cao, Zhongcheng Yang, et al.
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