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European Journal of Medicinal Chemistry|December 7, 2021
Design, synthesis, biochemical evaluation, radiolabeling and in vivo imaging with high affinity class-IIa histone deacetylase inhibitor for molecular imaging and targeted therapyNashaat Turkman, Daxing Liu, Isabella Pirola
European Journal of Medicinal Chemistry|December 9, 2021
Discovery of 9,10-dihydrophenanthrene derivatives as SARS-CoV-2 3CLpro inhibitors for treating COVID-19Jian-Wei Zhang, Yuan Xiong, Feng Wang, et al.
European Journal of Medicinal Chemistry|March 19, 2021
Discovery of novel and potent PARP/PI3K dual inhibitors for the treatment of cancerZhengyang Wu, Ying Bai, Jiaming Jin, et al.
European Journal of Medicinal Chemistry|March 21, 2021
Comprehensive study on potent and selective carbonic anhydrase inhibitors: Synthesis, bioactivities and molecular modelling studies of 4-(3-(2-arylidenehydrazine-1-carbonyl)-5-(thiophen-2-yl)-1H-pyrazole-1-yl) benzenesulfonamidesCem Yamali, Hiroshi Sakagami, Yoshihiro Uesawa, et al.
European Journal of Medicinal Chemistry|March 21, 2021
Poly ethylene glycol (PEG)-Related controllable and sustainable antidiabetic drug delivery systemsYupeng Fu, Ying Ding, Litao Zhang, et al.
European Journal of Medicinal Chemistry|September 5, 2022
Discovery of 1,2-diphenylethene derivatives as human DNA topoisomerase II catalytic inhibitors and antitumor agentsGuangsen Xu, Zhiying Li, Yanjiao Ding, et al.
European Journal of Medicinal Chemistry|September 5, 2022
Structure-based discovery of 1-(3-fluoro-5-(5-(3-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)phenyl)-3-(pyrimidin-5-yl)urea as a potent and selective nanomolar type-II PLK4 inhibitorYin Sun, Lin Wang, Yu Sun, et al.
European Journal of Medicinal Chemistry|September 8, 2022
Identification of L. infantum trypanothione synthetase inhibitors with leishmanicidal activity from a (non-biased) in-house chemical libraryMercedes Alcón-Calderón, Héctor de Lucio, Juan Carlos García-Soriano, et al.
European Journal of Medicinal Chemistry|September 8, 2022
Discovery of new macrophage M2 polarization modulators as multiple sclerosis treatment agents that enable the inflammation microenvironment remodelingJinxin Che, Dan Li, Wenxiang Hong, et al.
European Journal of Medicinal Chemistry|September 1, 2022
Development of 3α,7α-dihydroxy-6α-ethyl-24-nor-5β-cholan-23-sulfate sodium salt (INT-767): Process optimization, synthesis and characterization of metabolitesBruno Cerra, Francesco Venturoni, Maria Souma, et al.
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