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Investigational New Drugs|September 11, 2020
Phase 1 study of 2 high dose intensity schedules of the pan-Notch inhibitor crenigacestat (LY3039478) in combination with prednisone in patients with advanced or metastatic cancerAnalía Azaro, Capucine Baldini, Jordi Rodon, et al.
Investigational New Drugs|September 11, 2020
A novel LRRFIP1-ALK fusion in inflammatory myofibroblastic tumor of hip and response to crizotinibWeifeng Liu, Qianqian Duan, Lihua Gong, et al.
Investigational New Drugs|December 12, 2019
[HuArgI (co)-PEG5000]-induced arginine deprivation leads to autophagy dependent cell death in pancreatic cancer cellsNathalie Khalil, Ralph J Abi-Habib
Investigational New Drugs|January 4, 2020
A phase 2 clinical trial of the heat shock protein 90 (HSP 90) inhibitor ganetespib in patients with refractory advanced esophagogastric cancerLipika Goyal, Surendra Pal Chaudhary, Eunice L Kwak, et al.
Investigational New Drugs|January 4, 2020
NCI 6896: a phase I trial of vorinostat (SAHA) and isotretinoin (13-cis retinoic acid) in the treatment of patients with advanced renal cell carcinomaAna M Molina, Johannes C van der Mijn, Paul Christos, et al.
Investigational New Drugs|January 8, 2020
Patient selection for a developmental therapeutics program using whole genome and Transcriptome analysisJean-Michel Lavoie, Teresa Mitchell, Sung-Eun Lee, et al.
Investigational New Drugs|April 8, 2020
Phase 1 dose escalation trial of TAS-102 (trifluridine/tipiracil) and temozolomide in the treatment of advanced neuroendocrine tumorsNataliya V Uboha, Sam J Lubner, Noelle K LoConte, et al.
Investigational New Drugs|October 22, 2020
Phase I study assessing the mass balance, pharmacokinetics, and excretion of [14C]-pevonedistat, a NEDD8-activating enzyme inhibitor in patients with advanced solid tumorsXiaofei Zhou, Farhad Sedarati, Douglas V Faller, et al.
Investigational New Drugs|October 14, 2020
A phase Ib study of the highly selective MET-TKI savolitinib plus gefitinib in patients with EGFR-mutated, MET-amplified advanced non-small-cell lung cancerJin-Ji Yang, Jian Fang, Yong-Qian Shu, et al.
Investigational New Drugs|October 16, 2020
Recombinant human lactoferrin carrying humanized glycosylation exhibits antileukemia selective cytotoxicity, microfilament disruption, cell cycle arrest, and apoptosis activitiesSayuri Nakamura-Bencomo, Denisse A Gutierrez, Elisa Robles-Escajeda, et al.
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