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Investigational New Drugs|May 8, 2021
Benzyl and phenethyl isothiocyanates as promising epigenetic drug compounds by modulating histone acetylation and methylation marks in malignant melanomaMelina Mitsiogianni, Ioannis Anestopoulos, Sotiris Kyriakou, et al.
Investigational New Drugs|May 23, 2021
Gastrointestinal perforation following dabrafenib and trametinib administration in non-small cell lung carcinoma with BRAF V600E mutation: a case report and literature reviewYuri Shimada, Yuki Sato, Ryo Tachikawa, et al.
Investigational New Drugs|May 25, 2021
Chemoprevention of pancreatic cancer by inhibition of glutathione-S transferase P1Takahiro Kogawa, Yasushi Sato, Rai Shimoyama, et al.
Investigational New Drugs|June 17, 2015
First-in-human study of the toxicity, pharmacokinetics, and pharmacodynamics of CG200745, a pan-HDAC inhibitor, in patients with refractory solid malignanciesKyu-pyo Kim, Seong Joon Park, Jeong-Eun Kim, et al.
Investigational New Drugs|June 12, 2015
Phase II study of saracatinib (AZD0530) in patients with previously treated metastatic colorectal cancerS M Reddy, S Kopetz, J Morris, et al.
Investigational New Drugs|April 23, 2020
Targeting c-Met in triple negative breast cancer: preclinical studies using the c-Met inhibitor, Cpd ALaura Breen, Patricia B Gaule, Alexandra Canonici, et al.
Investigational New Drugs|September 8, 2021
Phase I study of weekly nab-paclitaxel plus carboplatin and concurrent thoracic radiotherapy in elderly patients with unresectable locally advanced non-small cell lung cancerShota Omori, Hideyuki Harada, Keita Mori, et al.
Investigational New Drugs|August 16, 2021
Anaphylactic shock in a small cell lung cancer patient receiving atezolizumab therapy: a rare but potentially fatal complicationYizhuo Zhao, Wei Peng, Muhammad Abbas, et al.
Investigational New Drugs|April 25, 2020
A phase I study of the VEGFR kinase inhibitor vatalanib in combination with the mTOR inhibitor, everolimus, in patients with advanced solid tumorsMojun Zhu, Julian R Molina, Grace K Dy, et al.
Investigational New Drugs|May 29, 2020
Chemosensitivity to HM90822, a novel synthetic IAP antagonist, is determined by p-AKT-inducible XIAP phosphorylation in human pancreatic cancer cellsSeung-Woo Hong, Jae-Sik Shin, Jai-Hee Moon, et al.
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