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Investigational New Drugs|August 30, 2024
Treatment response to durvalumab plus tremelimumab after progression with previous immune checkpoint inhibitor in unresectable hepatocellular carcinomaNami Mori, Nobuharu Tamaki, Shintaro Takaki, et al.
Investigational New Drugs|September 30, 2024
Gremlin1: a BMP antagonist with therapeutic potential in OncologyZhao Jin, Yanshuo Cao
Investigational New Drugs|October 5, 2024
Predictive value of ZFHX4 mutation for the efficacy of immune checkpoint inhibitors in non-small cell lung cancer and melanomaCong Fu, Haoran Gu, Lin Sun, et al.
Investigational New Drugs|October 10, 2024
Exposure-response relationships of venetoclax in combination with carfilzomib and dexamethasone in relapsed/refractory t(11;14) multiple myeloma patientsMohamed Ali Badawi, Benjamin Engelhardt, Edyta Dobkowska, et al.
Investigational New Drugs|August 21, 2024
Targeting multiple receptor tyrosine kinases with sitravatinib: A Phase 1b study in advanced renal cell carcinoma and castrate-resistant prostate cancerShubham Pant, Byoung Chul Cho, Christos E Kyriakopoulos, et al.
Investigational New Drugs|May 14, 2025
Evaluation of anti-leukemic activity and underlying mechanisms of the novel GSPT1 degrader AB138 in acute myeloid leukemiaLiqiang Wang, Xin Cai, Yang Kong, et al.
Investigational New Drugs|May 1, 2025
Safety, tolerability, and preliminary efficacy of nadunolimab, an anti-IL- 1 receptor accessory protein monoclonal antibody, in combination with pembrolizumab in patients with solid tumorsRoger B Cohen, Antonio Jimeno, Jennifer Hreno, et al.
Investigational New Drugs|April 30, 2025
Targeting Myc through BET-PROTAC elicits potent anti-lymphoma activity in diffuse large B cell lymphomaHui Wang, Ximei Wu, Jingjing Gao, et al.
Investigational New Drugs|April 25, 2025
MLN0905, a new inhibitor of Polo-like kinase 1 (PLK1), enhances the efficiency of lenalidomide in promoting the apoptosis of multiple myeloma cell linesReyhane Piri, Minoo Shahidi, Zahra Pooraskari, et al.
Investigational New Drugs|April 29, 2025
Discovery of potent CRBN-recruiting epidermal growth factor receptor (EGFR) degraders in vitroWenbo Hu, Jinmei He, Tianyu Xie, et al.
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