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Journal of Medicinal Chemistry|May 21, 2021
Discovery of Hyperstable Noncanonical Plant-Derived Epidermal Growth Factor Receptor Agonist and AnalogsShining Loo, Antony Kam, Bin Bin Li, et al.Journal of Medicinal Chemistry|May 20, 2021
The Expanding Role of Chemistry in Optimizing Proteins for Human Health ApplicationsBart I RomanJournal of Medicinal Chemistry|August 17, 2021
Targeting Rearranged during Transfection in Cancer: A Perspective on Small-Molecule Inhibitors and Their Clinical DevelopmentDebasmita Saha, Katie Rose Ryan, Naga Rajiv Lakkaniga, et al.Journal of Medicinal Chemistry|August 17, 2021
Structure-Activity Relationships of Triple-Action Platinum(IV) Prodrugs with Albumin-Binding Properties and Immunomodulating LigandsPhilipp Fronik, Isabella Poetsch, Alexander Kastner, et al.Journal of Medicinal Chemistry|August 5, 2021
Discovery, Synthesis, and Evaluation of Highly Selective Vascular Endothelial Growth Factor Receptor 3 (VEGFR3) Inhibitor for the Potential Treatment of Metastatic Triple-Negative Breast CancerYang Li, Gaoxia Yang, Jifa Zhang, et al.Journal of Medicinal Chemistry|August 10, 2021
Synthesis and Biological Evaluation of Novel Triazine Derivatives as Positive Allosteric Modulators of α7 Nicotinic Acetylcholine ReceptorsXintong Wang, Haoran Xiao, Jing Wang, et al.Journal of Medicinal Chemistry|August 10, 2021
Discovery of High-Affinity Inhibitors of the BPTF BromodomainTian Lu, Haibo Lu, Zhe Duan, et al.Journal of Medicinal Chemistry|August 10, 2021
Discovery of N-((3S,4S)-4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl-1H-pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous ToxicityJinxin Che, Xiaoyang Dai, Jian Gao, et al.Journal of Medicinal Chemistry|August 18, 2021
Identification of Betulinic Acid Derivatives as Potent TGR5 Agonists with Antidiabetic Effects via Humanized TGR5H88Y Mutant MiceYing Yun, Chenlu Zhang, Shimeng Guo, et al.Journal of Medicinal Chemistry|August 23, 2021
Potent Inhibition of Nicotinamide N-Methyltransferase by Alkene-Linked Bisubstrate Mimics Bearing Electron Deficient AromaticsYongzhi Gao, Matthijs J van Haren, Ned Buijs, et al.Pageof 3,134