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Journal of Medicinal Chemistry|August 20, 2004
Identification of 1,5-naphthyridine derivatives as a novel series of potent and selective TGF-beta type I receptor inhibitorsFrançoise Gellibert, James Woolven, Marie-Hélène Fouchet, et al.Journal of Medicinal Chemistry|August 20, 2004
Imidazoquinoxaline Src-family kinase p56Lck inhibitors: SAR, QSAR, and the discovery of (S)-N-(2-chloro-6-methylphenyl)-2-(3-methyl-1-piperazinyl)imidazo- [1,5-a]pyrido[3,2-e]pyrazin-6-amine (BMS-279700) as a potent and orally active inhibitor with excellent in vivo antiinflammatory activityPing Chen, Arthur M Doweyko, Derek Norris, et al.Journal of Medicinal Chemistry|March 19, 2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeabilityPekka Suomalainen, Christoffer Johans, Tim Söderlund, et al.Journal of Medicinal Chemistry|March 19, 2004
Synthesis and antitubulin activity of N1- and N4-substituted 3,5-dinitro sulfanilamides against African trypanosomes and LeishmaniaGautam Bhattacharya, Johnathan Herman, Dawn Delfín, et al.Journal of Medicinal Chemistry|July 23, 2004
Novel 2-aminotetralin and 3-aminochroman derivatives as selective serotonin 5-HT7 receptor agonists and antagonistsPär Holmberg, Daniel Sohn, Robert Leideborg, et al.Journal of Medicinal Chemistry|July 23, 2004
Contribution of ionization and lipophilicity to drug binding to albumin: a preliminary step toward biodistribution predictionGiuseppe Ermondi, Miriam Lorenti, Giulia CaronJournal of Medicinal Chemistry|July 23, 2004
A physiological model for the estimation of the fraction dose absorbed in humansStefan Willmann, Walter Schmitt, Jörg Keldenich, et al.Journal of Medicinal Chemistry|July 23, 2004
Synthesis and biological activity of new potential agonists for the human adenosine A2A receptorM Pilar Bosch, Francisco Campos, Itziar Niubó, et al.Journal of Medicinal Chemistry|June 25, 2004
Identification of non-phosphate-containing small molecular weight inhibitors of the tyrosine kinase p56 Lck SH2 domain via in silico screening against the pY + 3 binding siteNiu Huang, Ashish Nagarsekar, Guanjun Xia, et al.Journal of Medicinal Chemistry|June 25, 2004
New manzamine alkaloids from an Indo-Pacific sponge. Pharmacokinetics, oral availability, and the significant activity of several manzamines against HIV-I, AIDS opportunistic infections, and inflammatory diseasesMuhammad Yousaf, Nicholas L Hammond, Jiangnan Peng, et al.Pageof 3,137