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Journal of Medicinal Chemistry|November 11, 2010
Design, synthesis, and structure-activity relationships of 3-ethynyl-1H-indazoles as inhibitors of the phosphatidylinositol 3-kinase signaling pathwayElisa Barile, Surya K De, Coby B Carlson, et al.Journal of Medicinal Chemistry|January 14, 2011
X-ray crystal structure and binding mode analysis of human S-adenosylhomocysteine hydrolase complexed with novel mechanism-based inhibitors, haloneplanocin A analoguesKang Man Lee, Won Jun Choi, Yoonji Lee, et al.Journal of Medicinal Chemistry|January 12, 2011
Synthesis of cationic antimicrobial β(2,2)-amino acid derivatives with potential for oral administrationTerkel Hansen, Dominik Ausbacher, Gøril E Flaten, et al.Journal of Medicinal Chemistry|November 25, 2010
Diadenosine 5',5''-(boranated)polyphosphonate analogues as selective nucleotide pyrophosphatase/phosphodiesterase inhibitorsShay Eliahu, Joanna Lecka, Georg Reiser, et al.Journal of Medicinal Chemistry|November 18, 2010
Novel chimeric histone deacetylase inhibitors: a series of lapatinib hybrides as potent inhibitors of epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), and histone deacetylase activitySiavosh Mahboobi, Andreas Sellmer, Matthias Winkler, et al.Journal of Medicinal Chemistry|November 18, 2010
Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agentsNiamh M O'Boyle, Miriam Carr, Lisa M Greene, et al.Journal of Medicinal Chemistry|November 18, 2010
Discovery of 2-(6-{[(6-fluoroquinolin-2-yl)methyl]amino}bicyclo[3.1.0]hex-3-yl)-N-hydroxypyrimidine-5-carboxamide (CHR-3996), a class I selective orally active histone deacetylase inhibitorDavid Moffat, Sanjay Patel, Francesca Day, et al.Journal of Medicinal Chemistry|November 18, 2010
A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administrationDean A Heathcote, Hetal Patel, Sebastian H B Kroll, et al.Journal of Medicinal Chemistry|October 30, 2010
Preparation and evaluation of carborane analogues of tamoxifenMichael L Beer, Jennifer Lemon, John F ValliantJournal of Medicinal Chemistry|October 30, 2010
Novel potent orally active multitargeted receptor tyrosine kinase inhibitors: synthesis, structure-activity relationships, and antitumor activities of 2-indolinone derivativesTang Peng Cho, Su Yi Dong, Feng Jun, et al.Pageof 3,134