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Journal of Medicinal Chemistry|December 8, 2021
Development of a 1,2,4-Triazole-Based Lead Tankyrase Inhibitor: Part IIRuben G G Leenders, Shoshy Alam Brinch, Sven T Sowa, et al.Journal of Medicinal Chemistry|December 13, 2021
Discovery of the c-Jun N-Terminal Kinase Inhibitor CC-90001Mark A Nagy, Robert Hilgraf, Deborah S Mortensen, et al.Journal of Medicinal Chemistry|November 24, 2021
Structure-Based Design of Dual Partial Peroxisome Proliferator-Activated Receptor γ Agonists/Soluble Epoxide Hydrolase InhibitorsFelix F Lillich, Sabine Willems, Xiaomin Ni, et al.Journal of Medicinal Chemistry|November 24, 2021
Stapled Peptides Targeting SARS-CoV-2 Spike Protein HR1 Inhibit the Fusion of Virus to Its Cell ReceptorMengjun Zheng, Wei Cong, Haoran Peng, et al.Journal of Medicinal Chemistry|March 5, 2021
Discovery of a First-In-Class Small Molecule Antagonist against the Adrenomedullin-2 Receptor: Structure-Activity Relationships and OptimizationJean-Olivier Zirimwabagabo, Ameera B A Jailani, Paris Avgoustou, et al.Journal of Medicinal Chemistry|March 5, 2021
Design, Synthesis, and Biological Evaluation of Dexamethasone-Salvianolic Acid B Conjugates and Nanodrug Delivery against Cisplatin-Induced Hearing LossRuiqin Ye, Lifang Sun, Jinghui Peng, et al.Journal of Medicinal Chemistry|March 8, 2021
Generating Selective Leads for Mer Kinase Inhibitors-Example of a Comprehensive Lead-Generation StrategyJ Willem M Nissink, Sana Bazzaz, Carolyn Blackett, et al.Journal of Medicinal Chemistry|November 4, 2021
Small Molecules Targeting Activated Cdc42-Associated Kinase 1 (ACK1/TNK2) for the Treatment of CancersAoxue Wang, Junping Pei, Wen Shuai, et al.Journal of Medicinal Chemistry|November 5, 2021
MicroRNA-361-5p Aggravates Acute Pancreatitis by Promoting Interleukin-17A Secretion via Impairment of Nuclear Factor IA-Dependent Hes1 DownregulationMenglong Song, Yifan Wang, Ping Zhou, et al.Journal of Medicinal Chemistry|October 20, 2022
Development of Noncovalent Small-Molecule Keap1-Nrf2 Inhibitors by Fragment-Based Drug DiscoveryDilip Narayanan, Kim T Tran, Jakob S Pallesen, et al.Pageof 3,137