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Journal of Medicinal Chemistry|October 7, 2022
Natural Product-Inspired Targeted Protein Degraders: Advances and PerspectivesJiao Li, Zhenyu Cai, Xu-Wen Li, et al.Journal of Medicinal Chemistry|September 6, 2022
PDTAC: Targeted Photodegradation of GPX4 Triggers Ferroptosis and Potent Antitumor ImmunitySijin Liu, Xi Zhao, Sufang Shui, et al.Journal of Medicinal Chemistry|September 7, 2022
Discovery of Selenium-Containing STING Agonists as Orally Available Antitumor AgentsXi Feng, Lixia Pan, Zhiyu Qian, et al.Journal of Medicinal Chemistry|September 7, 2022
Optimization of the Prodrug Moiety of Remdesivir to Improve Lung Exposure/Selectivity and Enhance Anti-SARS-CoV-2 ActivityHongxiang Hu, Mohamed Dit Mady Traore, Ruiting Li, et al.Journal of Medicinal Chemistry|August 31, 2022
The Discovery of GSK3640254, a Next-Generation Inhibitor of HIV-1 MaturationAlicia Regueiro-Ren, Sing-Yuen Sit, Yan Chen, et al.Journal of Medicinal Chemistry|August 31, 2022
Structure-Based Design, Optimization, and Evaluation of Potent Stabilized Peptide Inhibitors Disrupting MTDH and SND1 InteractionHailing Chen, Meimiao Zhan, Jianbo Liu, et al.Journal of Medicinal Chemistry|June 1, 1987
Inhibition of the mammalian beta-lactamase renal dipeptidase (dehydropeptidase-I) by (Z)-2-(acylamino)-3-substituted-propenoic acidsD W Graham, W T Ashton, L Barash, et al.Journal of Medicinal Chemistry|December 27, 2021
Discovery of Orally Available Retinoic Acid Receptor-Related Orphan Receptor γ-t/Dihydroorotate Dehydrogenase Dual Inhibitors for the Treatment of Refractory Inflammatory Bowel DiseaseJi-An Chen, Hui Ma, Zehui Liu, et al.Journal of Medicinal Chemistry|December 27, 2021
Structure-Based and Knowledge-Informed Design of B-Raf Inhibitors Devoid of Deleterious PXR BindingMelanie Schneider, Vanessa Delfosse, Muriel Gelin, et al.Journal of Medicinal Chemistry|February 15, 2021
Preparation of Low Molecular Weight Heparin from a Remodeled Bovine Intestinal HeparinSultan N Baytas, Sony S Varghese, Weihua Jin, et al.Pageof 3,137