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Journal of Medicinal Chemistry|September 26, 2015
Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolines as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus MonkeysRainer E Martin, Johannes D Aebi, Benoit Hornsperger, et al.Journal of Medicinal Chemistry|January 15, 2015
2-(2-oxo-morpholin-3-yl)-acetamide derivatives as broad-spectrum antifungal agentsDorothée Bardiot, Karin Thevissen, Katrijn De Brucker, et al.Journal of Medicinal Chemistry|January 15, 2015
Discovery of 1H-pyrazol-3(2H)-ones as potent and selective inhibitors of protein kinase R-like endoplasmic reticulum kinase (PERK)Adrian L Smith, Kristin L Andrews, Holger Beckmann, et al.Journal of Medicinal Chemistry|January 15, 2015
Simple method provides resolution of albumin, lipoprotein, free fraction, and chylomicron to enhance the utility of protein binding assaysAdam H Brockman, Haley R Oller, Benoît Moreau, et al.Journal of Medicinal Chemistry|January 16, 2015
Stemistry: the control of stem cells in situ using chemistryStephen G Davies, Peter D Kennewell, Angela J Russell, et al.Journal of Medicinal Chemistry|January 16, 2015
Design, synthesis, and characterization of fatty acid derivatives of a dimeric peptide-based postsynaptic density-95 (PSD-95) inhibitorKlaus B Nissen, Julie J Andersen, Linda M Haugaard-Kedström, et al.Journal of Medicinal Chemistry|September 1, 2015
Characterization of 2,4-Diamino-6-oxo-1,6-dihydropyrimidin-5-yl Ureido Based Inhibitors of Trypanosoma brucei FolD and Testing for Antiparasitic ActivityThomas C Eadsforth, Andrea Pinto, Rosaria Luciani, et al.Journal of Medicinal Chemistry|September 3, 2015
Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary CancersVenkatram R Atigadda, Gang Xia, Anil Deshpande, et al.Journal of Medicinal Chemistry|September 23, 2015
Navigating CYP1A Induction and Arylhydrocarbon Receptor Agonism in Drug Discovery. A Case History with S1P1 AgonistsSimon J Taylor, Emmanuel H Demont, James Gray, et al.Journal of Medicinal Chemistry|September 23, 2015
Synthesis and Biological Evaluation of Manassantin Analogues for Hypoxia-Inducible Factor 1α InhibitionDo-Yeon Kwon, Hye Eun Lee, Douglas H Weitzel, et al.Pageof 3,137