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Journal of Medicinal Chemistry|September 24, 2015
Enhancement of Selectivity of an Organometallic Anticancer Agent by Redox ModulationIsolda Romero-Canelón, Magdalena Mos, Peter J SadlerJournal of Medicinal Chemistry|September 24, 2015
Probing the Molecular Interactions between CXC Chemokine Receptor 4 (CXCR4) and an Arginine-Based Tripeptidomimetic Antagonist (KRH-1636)Zack G Zachariassen, Stefanie Karlshøj, Bengt Erik Haug, et al.Journal of Medicinal Chemistry|September 24, 2015
Effective Two-Photon Excited Photodynamic Therapy of Xenograft Tumors Sensitized by Water-Soluble Bis(arylidene)cycloalkanone PhotosensitizersQianli Zou, Hongyou Zhao, Yuxia Zhao, et al.Journal of Medicinal Chemistry|August 11, 2015
The N-Terminal T-T Motif of a Third-Generation HIV-1 Fusion Inhibitor Is Not Required for Binding Affinity and Antiviral ActivityHuihui Chong, Zonglin Qiu, Yang Su, et al.Journal of Medicinal Chemistry|October 1, 2015
Targeted γ-Secretase Inhibition To Control the Notch Pathway in Renal DiseasesLucienne Juillerat-Jeanneret, Alexander Flohr, Manfred Schneider, et al.Journal of Medicinal Chemistry|December 25, 2015
Docking and Linking of Fragments To Discover Jumonji Histone Demethylase InhibitorsMagdalena Korczynska, Daniel D Le, Noah Younger, et al.Journal of Medicinal Chemistry|December 26, 2015
Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor AgentPaola Vianello, Oronza A Botrugno, Anna Cappa, et al.Journal of Medicinal Chemistry|December 26, 2015
Further Advances in Optimizing (2-Phenylcyclopropyl)methylamines as Novel Serotonin 2C Agonists: Effects on Hyperlocomotion, Prepulse Inhibition, and Cognition ModelsJianjun Cheng, Patrick M Giguere, Claire M Schmerberg, et al.Journal of Medicinal Chemistry|January 26, 2016
Role of Molecular Dynamics and Related Methods in Drug DiscoveryMarco De Vivo, Matteo Masetti, Giovanni Bottegoni, et al.Journal of Medicinal Chemistry|January 27, 2016
Discovery of (R)-6-(1-(8-Fluoro-6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one (AMG 337), a Potent and Selective Inhibitor of MET with High Unbound Target Coverage and Robust In Vivo Antitumor ActivityAlessandro A Boezio, Katrina W Copeland, Karen Rex, et al.Pageof 3,137