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Journal of Medicinal Chemistry|January 30, 2016
Oxadiazole-Based Cell Permeable Macrocyclic Transition State Inhibitors of Norovirus 3CL ProteaseVishnu C Damalanka, Yunjeong Kim, Kevin R Alliston, et al.Journal of Medicinal Chemistry|January 30, 2016
Mimicking of Arginine by Functionalized N(ω)-Carbamoylated Arginine As a New Broadly Applicable Approach to Labeled Bioactive Peptides: High Affinity Angiotensin, Neuropeptide Y, Neuropeptide FF, and Neurotensin Receptor Ligands As ExamplesMax Keller, Kilian K Kuhn, Jürgen Einsiedel, et al.Journal of Medicinal Chemistry|November 21, 2015
N'-3-(Trifluoromethyl)phenyl Derivatives of N-Aryl-N'-methylguanidines as Prospective PET Radioligands for the Open Channel of the N-Methyl-d-aspartate (NMDA) Receptor: Synthesis and Structure-Affinity RelationshipsGregory R Naumiec, Kimberley J Jenko, Sami S Zoghbi, et al.Journal of Medicinal Chemistry|November 24, 2015
N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase/Peroxisome Proliferator-Activated Receptor γ ModulatorsRené Blöcher, Christina Lamers, Sandra K Wittmann, et al.Journal of Medicinal Chemistry|January 16, 2016
Discovery of Highly Potent Inhibitors Targeting the Predominant Drug-Resistant S31N Mutant of the Influenza A Virus M2 Proton ChannelFang Li, Chunlong Ma, William F DeGrado, et al.Journal of Medicinal Chemistry|January 19, 2016
From Sphingosine Kinase to Dihydroceramide Desaturase: A Structure-Activity Relationship (SAR) Study of the Enzyme Inhibitory and Anticancer Activity of 4-((4-(4-Chlorophenyl)thiazol-2-yl)amino)phenol (SKI-II)Luigi Aurelio, Carmen V Scullino, Melissa R Pitman, et al.Journal of Medicinal Chemistry|January 20, 2016
Synthesis and Characterization of Fatty Acid Conjugates of Niacin and Salicylic AcidChi B Vu, Jean E Bemis, Ericka Benson, et al.Journal of Medicinal Chemistry|January 21, 2016
A Continuous, Fluorogenic Sirtuin 2 Deacylase Assay: Substrate Screening and Inhibitor EvaluationIacopo Galleano, Matthias Schiedel, Manfred Jung, et al.Journal of Medicinal Chemistry|January 21, 2016
Characterization of Multisubstituted Corticotropin Releasing Factor (CRF) Peptide Antagonists (Astressins)Judit Erchegyi, Lixin Wang, Jozsef Gulyas, et al.Journal of Medicinal Chemistry|January 21, 2016
Discovery of 2-((3-Amino-4-methylphenyl)amino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-ABL-053) as a Potent, Selective, and Orally Available BCR-ABL/SRC/p38 Kinase Inhibitor for Chronic Myeloid LeukemiaXiaofei Liang, Xiaochuan Liu, Beilei Wang, et al.Pageof 3,137