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Journal of Medicinal Chemistry|October 28, 2015
Identification of N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinical Trials for Hematological MalignanciesMatthew T Burger, Gisele Nishiguchi, Wooseok Han, et al.Journal of Medicinal Chemistry|November 3, 2015
Efficient Expression and Crystallization System of Cancer-Associated Carbonic Anhydrase Isoform IXJanis Leitans, Andris Kazaks, Agnese Balode, et al.Journal of Medicinal Chemistry|November 3, 2015
Further Optimization and Evaluation of Bioavailable, Mixed-Efficacy μ-Opioid Receptor (MOR) Agonists/δ-Opioid Receptor (DOR) Antagonists: Balancing MOR and DOR AffinitiesAubrie A Harland, Larisa Yeomans, Nicholas W Griggs, et al.Journal of Medicinal Chemistry|November 5, 2015
Small Molecule CXCR3 AntagonistsStephen P Andrews, Rhona J CoxJournal of Medicinal Chemistry|November 5, 2015
Design of Specific Serine Protease Inhibitors Based on a Versatile Peptide Scaffold: Conversion of a Urokinase Inhibitor to a Plasma Kallikrein InhibitorPeng Xu, Mingming Xu, Longguang Jiang, et al.Journal of Medicinal Chemistry|April 19, 2016
Probing the Anticancer Action of Oridonin with Fluorescent Analogues: Visualizing Subcellular Localization to MitochondriaShengtao Xu, Shanshan Luo, Hong Yao, et al.Journal of Medicinal Chemistry|May 1, 1989
2,3-Dihydro-5-benzofuranols as antioxidant-based inhibitors of leukotriene biosynthesisM L Hammond, I E Kopka, R A Zambias, et al.Journal of Medicinal Chemistry|May 1, 1989
Electrophilic derivatives of purines as irreversible inhibitors of A1 adenosine receptorsK A Jacobson, S Barone, U Kammula, et al.Journal of Medicinal Chemistry|May 1, 1989
New hydrogen-bond potentials for use in determining energetically favorable binding sites on molecules of known structureD N Boobbyer, P J Goodford, P M McWhinnie, et al.Journal of Medicinal Chemistry|May 1, 1989
Renal vasodilators. The role of the 4-substituent in isoquinolin-3-ol cardiovascular agents: 4-ureido derivatives of isoquinolin-3-ol with selective renal vasodilator propertiesR M Kanojia, O W Lever, J B Press, et al.Pageof 3,137