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Journal of Medicinal Chemistry|April 24, 2018
Highly Selective and Potent Ectonucleotide Pyrophosphatase-1 (NPP1) Inhibitors Based on Uridine 5'-Pα,α-Dithiophosphate AnaloguesVadim Zelikman, Julie Pelletier, Luba Simhaev, et al.Journal of Medicinal Chemistry|April 24, 2018
Discovery of MK-6169, a Potent Pan-Genotype Hepatitis C Virus NS5A Inhibitor with Optimized Activity against Common Resistance-Associated SubstitutionsWensheng Yu, Ling Tong, Oleg Selyutin, et al.Journal of Medicinal Chemistry|April 24, 2018
Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe SynthesisJames R Hill, Avril A B RobertsonJournal of Medicinal Chemistry|August 2, 2018
Discovery of 3-Benzyl-1-( trans-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) InhibitorsMasahiro Ito, Toshio Tanaka, Akinori Toita, et al.Journal of Medicinal Chemistry|August 2, 2018
Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological DisordersJustin S Cisar, Olivia D Weber, Jason R Clapper, et al.Journal of Medicinal Chemistry|August 4, 2018
Discovery of 4-Benzyloxybenzo[ d]isoxazole-3-amine Derivatives as Highly Selective and Orally Efficacious Human Sphingomyelin Synthase 2 Inhibitors that Reduce Chronic Inflammation in db/ db MiceMingguang Mo, Jintong Yang, Xian-Cheng Jiang, et al.Journal of Medicinal Chemistry|October 20, 2021
Interfering with the Tumor-Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 InhibitorsPasquale Russomanno, Giulia Assoni, Jussara Amato, et al.Journal of Medicinal Chemistry|October 21, 2021
Synthesis and Preclinical Evaluation of [18F]SiFA-PSMA Inhibitors in a Prostate Cancer ModelJustin J Bailey, Melinda Wuest, Michael Wagner, et al.Journal of Medicinal Chemistry|October 22, 2021
Berberine Molecular Recognition of the Parallel MYC G-Quadruplex in SolutionJonathan Dickerhoff, Nicole Brundridge, Scott A McLuckey, et al.Journal of Medicinal Chemistry|October 26, 2021
Chiral Cyclic Aliphatic Linkers as Building Blocks for Selective Dopamine D2 or D3 Receptor AgonistsFrancisco O Battiti, Saheem A Zaidi, Vsevolod Katritch, et al.Pageof 3,137