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Journal of Medicinal Chemistry|October 4, 2021
Inhibitor Combinations Reveal Wiring of the Proteostasis Network in Prostate Cancer CellsArielle Shkedi, Michael Adkisson, Andrew Schroeder, et al.Journal of Medicinal Chemistry|May 2, 2022
Identification of NVP-CLR457 as an Orally Bioavailable Non-CNS-Penetrant pan-Class IA Phosphoinositol-3-Kinase InhibitorRobin A Fairhurst, Pascal Furet, Patricia Imbach-Weese, et al.Journal of Medicinal Chemistry|May 2, 2022
Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis ActivityPreshendren Govender, Rudolf Müller, Kawaljit Singh, et al.Journal of Medicinal Chemistry|May 2, 2022
Design and Synthesis of Dual EZH2/BRD4 Inhibitors to Target Solid TumorsZhirong Guo, Yameng Sun, Liyun Liang, et al.Journal of Medicinal Chemistry|May 3, 2022
Development of Predictive Classification Models for Whole Cell Antimycobacterial Activity of BenzothiazinonesSebastian Schieferdecker, Freddy A Bernal, K Philip Wojtas, et al.Journal of Medicinal Chemistry|May 3, 2022
Differential Modulation of Nuclear Receptor LRH-1 through Targeting Buried and Surface Regions of the Binding PocketMichael L Cato, Jeffery L Cornelison, Racheal M Spurlin, et al.Journal of Medicinal Chemistry|April 27, 2022
Discovery of 2-Amino-3-cyanothiophene Derivatives as Potent STAT3 Inhibitors for the Treatment of Osteosarcoma Growth and MetastasisWangrui Jin, Tao Zhang, Wenbo Zhou, et al.Journal of Medicinal Chemistry|April 28, 2022
Development of Azaindole-Based Frameworks as Potential Antiviral Agents and Their Future PerspectivesUrvashi, J B Senthil Kumar, Parthasarathi Das, et al.Journal of Medicinal Chemistry|April 25, 2022
Engaging the Medicinal Chemists of TomorrowLori Ferrins, Erika Araujo, Matthew W Boudreau, et al.Journal of Medicinal Chemistry|April 25, 2022
Parallel Optimization of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain InhibitorDuncan C Miller, Tristan Reuillon, Lauren Molyneux, et al.Pageof 3,137