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Journal of Medicinal Chemistry|March 23, 2011
Single photon emission computed tomography/positron emission tomography imaging and targeted radionuclide therapy of melanoma: new multimodal fluorinated and iodinated radiotracersAurélie Maisonial, Bertrand Kuhnast, Janine Papon, et al.Journal of Medicinal Chemistry|April 15, 2011
SHAFTS: a hybrid approach for 3D molecular similarity calculation. 2. Prospective case study in the discovery of diverse p90 ribosomal S6 protein kinase 2 inhibitors to suppress cell migrationWeiqiang Lu, Xiaofeng Liu, Xianwen Cao, et al.Journal of Medicinal Chemistry|April 15, 2011
Immunosuppressive but non-LasR-inducing analogues of the Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl)-l-homoserine lactoneGopal P Jadhav, Siri Ram Chhabra, Gary Telford, et al.Journal of Medicinal Chemistry|April 8, 2011
Novel benzo[b]thiophene derivatives as new potential antidepressants with rapid onset of actionLuis Berrade, Bárbara Aisa, María J Ramirez, et al.Journal of Medicinal Chemistry|April 6, 2011
Potent bivalent Smac mimetics: effect of the linker on binding to inhibitor of apoptosis proteins (IAPs) and anticancer activityHaiying Sun, Liu Liu, Jianfeng Lu, et al.Journal of Medicinal Chemistry|March 25, 2011
Reversible competitive α-ketoheterocycle inhibitors of fatty acid amide hydrolase containing additional conformational constraints in the acyl side chain: orally active, long-acting analgesicsCyrine Ezzili, Mauro Mileni, Nicholas McGlinchey, et al.Journal of Medicinal Chemistry|March 25, 2011
Small molecule inhibitors of retinoic acid 4-hydroxylase (CYP26): synthesis and biological evaluation of imidazole methyl 3-(4-(aryl-2-ylamino)phenyl)propanoatesMohamed S Gomaa, Caroline E Bridgens, Ahmed S Aboraia, et al.Journal of Medicinal Chemistry|March 25, 2011
Impact of the nature of the substituent at the 3-position of 4H-1,2,4-benzothiadiazine 1,1-dioxides on their opening activity toward ATP-sensitive potassium channelsBernard Pirotte, Pascal de Tullio, Stéphane Boverie, et al.Journal of Medicinal Chemistry|March 19, 2011
Discovery of orally active carboxylic acid derivatives of 2-phenyl-5-trifluoromethyloxazole-4-carboxamide as potent diacylglycerol acyltransferase-1 inhibitors for the potential treatment of obesity and diabetesYimin Qian, Stanley J Wertheimer, Mushtaq Ahmad, et al.Journal of Medicinal Chemistry|March 30, 2011
Discovery and preclinical evaluation of a novel class of cytotoxic propynoic acid carbamoyl methyl amides (PACMAs)Roppei Yamada, Xuefei Cao, Alexey N Butkevich, et al.Pageof 3,134