Showing results (2661-2670 of 31,410) with videos related to
Sort By:
Pageof 3,141
Journal of Medicinal Chemistry|March 4, 2009
14 beta-O-cinnamoylnaltrexone and related dihydrocodeinones are mu opioid receptor partial agonists with predominant antagonist activityH Moynihan, A R Jales, B M Greedy, et al.Journal of Medicinal Chemistry|March 5, 2009
Dual inhibitors of phosphodiesterase-4 and serotonin reuptakeJohn R Cashman, Troy Voelker, Han-Ting Zhang, et al.Journal of Medicinal Chemistry|March 5, 2009
Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding modeKevin Qian, Lian Wang, Charles L Cywin, et al.Journal of Medicinal Chemistry|March 5, 2009
Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based designDouglas S Williamson, Jenifer Borgognoni, Alexandra Clay, et al.Journal of Medicinal Chemistry|March 6, 2009
Docking model of drug binding to the human ether-à-go-go potassium channel guided by tandem dimer mutant patch-clamp data: a synergic approachYumi N Imai, Sunghi Ryu, Shigetoshi OikiJournal of Medicinal Chemistry|January 8, 2009
Design, synthesis, and cytoprotective effect of 2-aminothiazole analogues as potent poly(ADP-ribose) polymerase-1 inhibitorsWen-Ting Zhang, Jin-Lan Ruan, Peng-Fei Wu, et al.Journal of Medicinal Chemistry|May 15, 2009
Discovery of low nanomolar and subnanomolar inhibitors of the mycobacterial beta-carbonic anhydrases Rv1284 and Rv3273Ozlen Güzel, Alfonso Maresca, Andrea Scozzafava, et al.Journal of Medicinal Chemistry|May 16, 2009
Discovery of N-{N-[(3-cyanophenyl)sulfonyl]-4(R)-cyclobutylamino-(L)-prolyl}-4-[(3',5'-dichloroisonicotinoyl) amino]-(L)-phenylalanine (MK-0668), an extremely potent and orally active antagonist of very late antigen-4Linus S Lin, Thomas Lanza, James P Jewell, et al.Journal of Medicinal Chemistry|May 16, 2009
Discovery of a potent class I selective ketone histone deacetylase inhibitor with antitumor activity in vivo and optimized pharmacokinetic propertiesOlaf Kinzel, Laura Llauger-Bufi, Giovanna Pescatore, et al.Journal of Medicinal Chemistry|June 26, 2009
Octahydropyrrolo[3,4-c]pyrrole: a diamine scaffold for construction of either alpha4beta2 or alpha7-selective nicotinic acetylcholine receptor (nAChR) ligands. Substitutions that switch subtype selectivityWilliam H Bunnelle, Karin R Tietje, Jennifer M Frost, et al.Pageof 3,141