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Journal of Medicinal Chemistry|September 1, 2016
Preparation, Antiepileptic Activity, and Cardiovascular Safety of Dihydropyrazoles as Brain-Penetrant T-Type Calcium Channel BlockersLubos Remen, Olivier Bezençon, Lloyd Simons, et al.Journal of Medicinal Chemistry|September 1, 2016
Discovery of 8-Trifluoromethyl-3-cyclopropylmethyl-7-[(4-(2,4-difluorophenyl)-1-piperazinyl)methyl]-1,2,4-triazolo[4,3-a]pyridine (JNJ-46356479), a Selective and Orally Bioavailable mGlu2 Receptor Positive Allosteric Modulator (PAM)Jose María Cid, Gary Tresadern, Juan Antonio Vega, et al.Journal of Medicinal Chemistry|May 16, 2017
Interrogating the Roles of Post-Translational Modifications of Non-Histone ProteinsZakey Yusuf Buuh, Zhigang Lyu, Rongsheng E WangJournal of Medicinal Chemistry|May 19, 2017
Design and Synthesis of Soluble and Cell-Permeable PI3Kδ Inhibitors for Long-Acting Inhaled AdministrationMatthew W D Perry, Karin Björhall, Britta Bonn, et al.Journal of Medicinal Chemistry|May 20, 2017
Double-Winged 3-Hydroxypyrimidine-2,4-diones: Potent and Selective Inhibition against HIV-1 RNase H with Significant Antiviral ActivitySanjeev Kumar V Vernekar, Jing Tang, Bulan Wu, et al.Journal of Medicinal Chemistry|September 16, 2016
Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo EfficacyBeatriz Baragaña, Neil R Norcross, Caroline Wilson, et al.Journal of Medicinal Chemistry|May 26, 2017
Identification of a Potent, Selective, and Efficacious Phosphatidylinositol 3-Kinase δ (PI3Kδ) Inhibitor for the Treatment of Immunological DisordersQingjie Liu, Qing Shi, David Marcoux, et al.Journal of Medicinal Chemistry|September 1, 1985
Acylmorphinans. A novel class of potent analgesic agentsE Mohacsi, J O'Brien, J Blount, et al.Journal of Medicinal Chemistry|June 27, 2017
Prodrugs of Pyrazolo[3,4-d]pyrimidines: From Library Synthesis to Evaluation as Potential Anticancer Agents in an Orthotopic Glioblastoma ModelGiulia Vignaroli, Giulia Iovenitti, Claudio Zamperini, et al.Journal of Medicinal Chemistry|June 7, 2017
Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2Misa Iwatani-Yoshihara, Masahiro Ito, Michael G Klein, et al.Pageof 3,141