Showing results (731-740 of 31,337) with videos related to
Sort By:
Pageof 3,134
Journal of Medicinal Chemistry|November 28, 2006
Fragment-based drug design: how big is too big?Philip J HajdukJournal of Medicinal Chemistry|November 28, 2006
A 2.13 A structure of E. coli dihydrofolate reductase bound to a novel competitive inhibitor reveals a new binding surface involving the M20 loop regionRachael L Summerfield, Denis M Daigle, Stanislas Mayer, et al.Journal of Medicinal Chemistry|November 28, 2006
Synthetic inhibitors of cytochrome P-450 2A6: inhibitory activity, difference spectra, mechanism of inhibition, and protein cocrystallizationJason K Yano, Travis T Denton, Matthew A Cerny, et al.Journal of Medicinal Chemistry|November 28, 2006
Synthesis of DNA-directed pyrrolidinyl and piperidinyl confined alkylating chloroalkylaminoanthraquinones: potential for development of tumor-selective N-oxidesKlaus Pors, Steven D Shnyder, Paul H Teesdale-Spittle, et al.Journal of Medicinal Chemistry|November 28, 2006
Carbonic anhydrase inhibitors: clash with Ala65 as a means for designing inhibitors with low affinity for the ubiquitous isozyme II, exemplified by the crystal structure of the topiramate sulfamide analogueJean-Yves Winum, Claudia Temperini, Khaled El Cheikh, et al.Journal of Medicinal Chemistry|November 28, 2006
Synthesis and structure-activity relationships of uracil nucleotide derivatives and analogues as agonists at human P2Y2, P2Y4, and P2Y6 receptorsAli El-Tayeb, Aidong Qi, Christa E MüllerJournal of Medicinal Chemistry|November 28, 2006
WB4101-related compounds: new, subtype-selective alpha1-adrenoreceptor antagonists (or inverse agonists?)Marco Pallavicini, Roberta Budriesi, Laura Fumagalli, et al.Journal of Medicinal Chemistry|November 28, 2006
Substituted trans-stilbenes, including analogues of the natural product resveratrol, inhibit the human tumor necrosis factor alpha-induced activation of transcription factor nuclear factor kappaBJustin J Heynekamp, Waylon M Weber, Lucy A Hunsaker, et al.Journal of Medicinal Chemistry|November 28, 2006
Synthesis and radioligand binding studies of methoxylated 1,2,3,4-tetrahydroisoquinolinium derivatives as ligands of the apamin-sensitive Ca2+-activated K+ channelsAmaury Graulich, Jacqueline Scuvée-Moreau, Livia Alleva, et al.Journal of Medicinal Chemistry|November 28, 2006
Discovering inhibitors of human sirtuin type 2: novel structural scaffoldsAnu J Tervo, Tiina Suuronen, Sergiy Kyrylenko, et al.Pageof 3,134