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Journal of Medicinal Chemistry|May 10, 2021
Kinase Inhibitors as Underexplored Antiviral AgentsJavier García-Cárceles, Elena Caballero, Carmen Gil, et al.Journal of Medicinal Chemistry|May 4, 2021
Improvement of Oral Bioavailability of Pyrazolo-Pyridone Inhibitors of the Interaction of DCN1/2 and UBE2MHo Shin Kim, Jared T Hammill, Daniel C Scott, et al.Journal of Medicinal Chemistry|May 18, 2021
Designing Out PXR Activity on Drug Discovery Projects: A Review of Structure-Based Methods, Empirical and Computational ApproachesAdrian Hall, Hugues Chanteux, Karelle Ménochet, et al.Journal of Medicinal Chemistry|May 19, 2021
Identification of an N-acylated-DArg-Leu-NH2 Dipeptide as a Highly Selective Neuropeptide FF1 Receptor Antagonist That Potently Prevents Opioid-Induced HyperalgesiaRaphaëlle Quillet, Séverine Schneider, Valérie Utard, et al.Journal of Medicinal Chemistry|May 21, 2021
Photocytotoxicity of Thiophene- and Bithiophene-Dipicolinato Luminescent Lanthanide ComplexesCarime V Rodrigues, Katherine R Johnson, Vincent C Lombardi, et al.Journal of Medicinal Chemistry|May 21, 2021
Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3',3'-c-Di(2'F,2'dAMP)Markéta Pimková Polidarová, Petra Břehová, Martin Maxmilian Kaiser, et al.Journal of Medicinal Chemistry|April 30, 2021
Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity against Fluoroquinolone-Resistant Gram-Positive BacteriaGuillaume Lapointe, Colin K Skepper, Lauren M Holder, et al.Journal of Medicinal Chemistry|May 3, 2021
Discovery of Novel and Potent N-Methyl-d-aspartate Receptor Positive Allosteric Modulators with Antidepressant-like Activity in Rodent ModelsZhongtang Li, Guanxing Cai, Fan Fang, et al.Journal of Medicinal Chemistry|May 3, 2021
Structure-Based Discovery of Pyrimidine Aminobenzene Derivatives as Potent Oral Reversal Agents against P-gp- and BCRP-Mediated Multidrug ResistanceQianqian Qiu, Feng Zou, Huilan Li, et al.Journal of Medicinal Chemistry|May 4, 2021
Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In VivoTamara Halkina, Jaclyn L Henderson, Edward Y Lin, et al.Pageof 3,134