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Journal of Medicinal Chemistry|September 16, 2021
Discovery of AS-1763: A Potent, Selective, Noncovalent, and Orally Available Inhibitor of Bruton's Tyrosine KinaseWataru Kawahata, Tokiko Asami, Takao Kiyoi, et al.Journal of Medicinal Chemistry|September 13, 2021
Combining Electrospray Mass Spectrometry (ESI-MS) and Computational Techniques in the Assessment of G-Quadruplex Ligands: A Hybrid Approach to Optimize Hit DiscoveryGiovanni Ribaudo, Alberto Ongaro, Erika Oselladore, et al.Journal of Medicinal Chemistry|September 13, 2021
Optimization of 4,6-Disubstituted Pyrido[3,2-d]pyrimidines as Dual MNK/PIM Inhibitors to Inhibit Leukemia Cell GrowthYu Han, Huimin Zhang, Shuxiang Wang, et al.Journal of Medicinal Chemistry|September 7, 2021
Synthesis and Biological Evaluation of C-17-Amino-Substituted Pyrazole-Fused Betulinic Acid Derivatives as Novel Agents for Osteoarthritis TreatmentJie Wang, Wenhui Wei, Xiaofei Zhang, et al.Journal of Medicinal Chemistry|September 7, 2021
Searching Geometric Patterns in Protein Binding Sites and Their Application to Data Mining in Protein Kinase StructuresJoel Graef, Christiane Ehrt, Konrad Diedrich, et al.Journal of Medicinal Chemistry|September 8, 2021
Discovery of Milvexian, a High-Affinity, Orally Bioavailable Inhibitor of Factor XIa in Clinical Studies for Antithrombotic TherapyAndrew K Dilger, Kumar B Pabbisetty, James R Corte, et al.Journal of Medicinal Chemistry|September 3, 2021
Discovery of Potent Antiallergic Agents Based on an o-Aminopyridinyl Alkynyl ScaffoldZhicheng Xie, Caigui Xiang, Xin Li, et al.Journal of Medicinal Chemistry|September 10, 2021
Discovery of a Potent Glutathione Peroxidase 4 Inhibitor as a Selective Ferroptosis InducerCongjun Xu, Zhanghong Xiao, Jing Wang, et al.Journal of Medicinal Chemistry|September 10, 2021
α/Sulfono-γ-AApeptide Hybrid Analogues of Glucagon with Enhanced Stability and Prolonged In Vivo ActivityPeng Sang, Hongxiang Zeng, Candy Lee, et al.Journal of Medicinal Chemistry|September 2, 2021
Potent Inhibition of HIF1α and p300 Interaction by a Constrained Peptide Derived from CITED2Xuan Qin, Hailing Chen, Licheng Tu, et al.Pageof 3,134