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Journal of Pharmacokinetics and Pharmacodynamics|June 21, 2024
Advancing cancer drug development with mechanistic mathematical modeling: bridging the gap between theory and practiceAlexander Kulesza, Claire Couty, Paul Lemarre, et al.Journal of Pharmacokinetics and Pharmacodynamics|May 25, 2024
ChatGPT and Gemini large language models for pharmacometrics with NONMEM: commentHinpetch Daungsupawong, Viroj WiwanitkitJournal of Pharmacokinetics and Pharmacodynamics|April 19, 2024
Target-mediated drug disposition model for drugs with N > 2 binding sites that bind to a target with one binding siteLeonid Gibiansky, Chee M Ng, Ekaterina GibianskyJournal of Pharmacokinetics and Pharmacodynamics|December 9, 2025
Aggregate data modelling: A fast implementation for fitting pharmacometrics models to summary-level data in RHidde van de Beek, Pyry A J Välitalo, J G Coen van Hasselt, et al.Journal of Pharmacokinetics and Pharmacodynamics|December 17, 2024
QSP modeling of a transiently inactivating antibody-drug conjugate highlights benefit of short antibody half lifeEshita Khera, Lekshmi Dharmarajan, Dominik Hainzl, et al.Journal of Pharmacokinetics and Pharmacodynamics|December 20, 2024
Novel endpoints based on tumor size ratio to support early clinical decision-making in oncology drug-developmentShubhadeep Chakraborty, Kshitij Aggarwal, Marzana Chowdhury, et al.Journal of Pharmacokinetics and Pharmacodynamics|January 17, 2025
A physiologically-based quantitative systems pharmacology model for mechanistic understanding of the response to alogliptin and its application in patients with renal impairmentChaozhuang Shen, Haitang Xie, Xuehua Jiang, et al.Journal of Pharmacokinetics and Pharmacodynamics|February 8, 2025
Reliability of in vitro data for the mechanistic prediction of brain extracellular fluid pharmacokinetics of P-glycoprotein substrates in vivo; are we scaling correctly?Daan W van Valkengoed, Makoto Hirasawa, Vivi Rottschäfer, et al.Journal of Pharmacokinetics and Pharmacodynamics|December 10, 2024
Comparison of the power and type 1 error of total score models for drug effect detection in clinical trialsElham Haem, Mats O Karlsson, Sebastian UeckertJournal of Pharmacokinetics and Pharmacodynamics|December 10, 2024
Model-informed approach to estimate treatment effect in placebo-controlled clinical trials using an artificial intelligence-based propensity weighting methodology to account for non-specific responses to treatmentRoberto Gomeni, F Bressolle-GomeniPageof 107