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Journal of Pharmacokinetics and Pharmacodynamics|December 25, 2012
Dose selection using a semi-mechanistic integrated glucose-insulin-glucagon model: designing phase 2 trials for a novel oral glucokinase activatorXin Zhang, Karen Schneck, Juliana Bue-Valleskey, et al.Journal of Pharmacokinetics and Pharmacodynamics|August 28, 2013
Optimizing disease progression study designs for drug effect discriminationSebastian Ueckert, Stefanie Hennig, Joakim Nyberg, et al.Journal of Pharmacokinetics and Pharmacodynamics|October 8, 2013
A mechanistic pharmacodynamic model of IRAK-4 drug inhibition in the Toll-like receptor pathwayRyan P Nolan, Andrea G Bree, Anup ZutshiJournal of Pharmacokinetics and Pharmacodynamics|June 5, 2013
A general model-based design of experiments approach to achieve practical identifiability of pharmacokinetic and pharmacodynamic modelsFederico Galvanin, Carlo C Ballan, Massimiliano Barolo, et al.Journal of Pharmacokinetics and Pharmacodynamics|April 26, 2013
Incorporation of ABCB1-mediated transport into a physiologically-based pharmacokinetic model of docetaxel in miceSusan F Hudachek, Daniel L GustafsonJournal of Pharmacokinetics and Pharmacodynamics|November 27, 2012
Applications of minimal physiologically-based pharmacokinetic modelsYanguang Cao, William J JuskoJournal of Pharmacokinetics and Pharmacodynamics|August 22, 2014
Modeling of delays in PKPD: classical approaches and a tutorial for delay differential equationsGilbert Koch, Wojciech Krzyzanski, Juan Jose Pérez-Ruixo, et al.Journal of Pharmacokinetics and Pharmacodynamics|November 8, 2014
Pharmacokinetic-pharmacodynamic modeling for reduction of hepatic apolipoprotein B mRNA and plasma total cholesterol after administration of antisense oligonucleotide in miceRyosuke Shimizu, Mikiko Kitade, Takashi Kobayashi, et al.Journal of Pharmacokinetics and Pharmacodynamics|October 31, 2014
In vitro simulation of in vivo pharmacokinetic model with intravenous administration via flow rate modulationYuan-Cheng Chen, Wang Liang, Jia-Li Hu, et al.Journal of Pharmacokinetics and Pharmacodynamics|June 17, 2008
Modeling time variant distributions of cellular lifespans: increases in circulating reticulocyte lifespans following double phlebotomies in sheepKevin J Freise, John A Widness, Robert L Schmidt, et al.Pageof 107