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Molecular Cancer Therapeutics|June 30, 2011
Compensatory pathways induced by MEK inhibition are effective drug targets for combination therapy against castration-resistant prostate cancerDaniel Gioeli, Winfried Wunderlich, Judith Sebolt-Leopold, et al.
Molecular Cancer Therapeutics|March 31, 2011
Evasion mechanisms to Igf1r inhibition in rhabdomyosarcomaJinu Abraham, Suresh I Prajapati, Koichi Nishijo, et al.
Molecular Cancer Therapeutics|April 5, 2011
Hypoxia induces genomic DNA demethylation through the activation of HIF-1α and transcriptional upregulation of MAT2A in hepatoma cellsQuanyan Liu, Li Liu, Yuhong Zhao, et al.
Molecular Cancer Therapeutics|December 20, 2011
βII-tubulin and βIII-tubulin mediate sensitivity to peloruside A and laulimalide, but not paclitaxel or vinblastine, in human ovarian carcinoma cellsArun Kanakkanthara, Peter T Northcote, John H Miller
Molecular Cancer Therapeutics|December 14, 2011
New insights into molecular mechanisms of sunitinib-associated side effectsGuadalupe Aparicio-Gallego, Moisés Blanco, Angélica Figueroa, et al.
Molecular Cancer Therapeutics|December 7, 2011
MEK1/2 inhibitor selumetinib (AZD6244) inhibits growth of ovarian clear cell carcinoma in a PEA-15-dependent manner in a mouse xenograft modelChandra Bartholomeusz, Tetsuro Oishi, Hitomi Saso, et al.
Molecular Cancer Therapeutics|December 7, 2011
Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapyWeiwen Ying, Zhenjian Du, Lijun Sun, et al.
Molecular Cancer Therapeutics|November 8, 2011
Rapamycin induces Bad phosphorylation in association with its resistance to human lung cancer cellsYan Liu, Shi-Yong Sun, Taofeek K Owonikoko, et al.
Molecular Cancer Therapeutics|November 8, 2011
Tumor suppressor microRNA-493 decreases cell motility and migration ability in human bladder cancer cells by downregulating RhoC and FZD4Koji Ueno, Hiroshi Hirata, Shahana Majid, et al.
Molecular Cancer Therapeutics|November 16, 2011
Gene expression profile in response to doxorubicin-rapamycin combined treatment of HER-2-overexpressing human mammary epithelial cell linesAdriana Priscila Trapé, Maria Lucia Hirata Katayama, Rosimeire Aparecida Roela, et al.
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