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Molecular Cancer Therapeutics|June 23, 2021
SHP2 Inhibition Enhances the Effects of Tyrosine Kinase Inhibitors in Preclinical Models of Treatment-naïve ALK-, ROS1-, or EGFR-altered Non-small Cell Lung CancerHirohisa Kano, Eiki Ichihara, Hiromi Watanabe, et al.
Molecular Cancer Therapeutics|June 23, 2021
Development of a High-throughput NanoBRET Screening Platform to Identify Modulators of the RAS/RAF InteractionDavid E Durrant, Emily A Smith, Ekaterina I Goncharova, et al.
Molecular Cancer Therapeutics|January 9, 2023
Discovery of a Novel ATP-Competitive MEK Inhibitor DS03090629 that Overcomes Resistance Conferred by BRAF Overexpression in BRAF-Mutated MelanomaKohei Takano, Yoichi Munehira, Mana Hatanaka, et al.
Molecular Cancer Therapeutics|June 1, 2022
Covalent ERα Antagonist H3B-6545 Demonstrates Encouraging Preclinical Activity in Therapy-Resistant Breast CancerCraig Furman, Xiaoling Puyang, Zhaojie Zhang, et al.
Molecular Cancer Therapeutics|June 3, 2022
Lurbinectedin Inhibits the EWS-WT1 Transcription Factor in Desmoplastic Small Round Cell TumorJenna M Gedminas, Rebecca Kaufman, Elissa A Boguslawski, et al.
Molecular Cancer Therapeutics|June 3, 2022
Trastuzumab Deruxtecan, Antibody-Drug Conjugate Targeting HER2, Is Effective in Pediatric Malignancies: A Report by the Pediatric Preclinical Testing ConsortiumPooja Hingorani, Wendong Zhang, Zhongting Zhang, et al.
Molecular Cancer Therapeutics|June 6, 2022
Optimization and Characterization of a Bone Culture Model to Study Prostate Cancer Bone MetastasisYi-Hsuan Wu, Zbigniew Gugala, Megan M Barry, et al.
Molecular Cancer Therapeutics|May 5, 2022
A High-Throughput Screening Platform Identifies Novel Combination Treatments for Malignant Peripheral Nerve Sheath TumorsJuana Fernández-Rodríguez, Edgar Creus-Bachiller, Xiaohu Zhang, et al.
Molecular Cancer Therapeutics|October 9, 2021
Molecular Characteristics of Repotrectinib That Enable Potent Inhibition of TRK Fusion Proteins and Resistant MutationsBrion W Murray, Evan Rogers, Dayong Zhai, et al.
Molecular Cancer Therapeutics|October 13, 2021
SMARCA4: Implications of an Altered Chromatin-Remodeling Gene for Cancer Development and TherapyKristina Mardinian, Jacob J Adashek, Gregory P Botta, et al.
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