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Nature Biotechnology|January 19, 2026
Engineered living glues secrete therapeutic proteins for treatment of inflammatory bowel diseaseChanghao Ge, Shanshan Jiang, Xiaomin Dong, et al.Nature Biotechnology|January 19, 2026
An engineered UGA suppressor tRNA gene for disease-agnostic AAV deliveryMengyao Xu, Hao Liu, Jiaming Wang, et al.Nature Biotechnology|February 10, 2026
Identifying 3D signal overlaps in spatial transcriptomics data with ovrlpySebastian Tiesmeyer, Niklas Müller-Bötticher, Alexander Malt, et al.Nature Biotechnology|February 4, 2026
Pilot phase clinical trial of a wearable, electrochemical aptamer-based patch for continuous drug concentration measurementMarsilea A Booth, Murat K Erdal, Mikel Larson, et al.Nature Biotechnology|November 18, 2025
Extensive restoration of forelimb function in primates with spinal cord injury by neural stem cell transplantationEleni Sinopoulou, Ephron S Rosenzweig, John H Brock, et al.Nature Biotechnology|January 17, 2025
Multiplexed inhibition of immunosuppressive genes with Cas13d for combinatorial cancer immunotherapyFeifei Zhang, Ryan D Chow, Emily He, et al.Nature Biotechnology|February 17, 2025
The reverse transcriptase domain of prime editors contributes to DNA repair in mammalian cellsChunwei Zheng, Gangming Zhang, Lilia J Dean, et al.Nature Biotechnology|December 13, 2024
Targeting peptide antigens using a multiallelic MHC I-binding systemHaotian Du, Leena Mallik, Daniel Hwang, et al.Nature Biotechnology|December 11, 2024
Intestinal mucosal barrier repair and immune regulation with an AI-developed gut-restricted PHD inhibitorYanyun Fu, Xiao Ding, Man Zhang, et al.Nature Biotechnology|January 3, 2024
IL-10-expressing CAR T cells resist dysfunction and mediate durable clearance of solid tumors and metastasesYang Zhao, Jiangqing Chen, Massimo Andreatta, et al.Pageof 380