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Nature Chemical Biology|January 6, 2026
A single allosteric site merges activation, modulation and inhibition in TRPM5Zheng Ruan, Junuk Lee, Yangyang Li, et al.Nature Chemical Biology|January 6, 2026
Allosteric activation of RNF20/RNF40-RAD6A-mediated H2BK120 monoubiquitylation by H2BS112 GlcNAcylationZhiheng Deng, Shixian Tao, Yunxiang Du, et al.Nature Chemical Biology|January 9, 2026
LipoID profiles lipid droplet interactions and identifies interorganelle regulatorsHengke Guo, Wang Wan, Yanan Huang, et al.Nature Chemical Biology|January 6, 2026
Programmable cell-cell adhesion in synthetic yeast communities for improved bioproductionHaohong Chen, Huadong Peng, Tom Ellis, et al.Nature Chemical Biology|December 30, 2025
PCMT1 generates the C-terminal cyclic imide degron on CRBN substratesZhenguang Zhao, Wenqing Xu, Ethan Yang Feng, et al.Nature Chemical Biology|January 13, 2026
GCN5-ERK lactylation-phosphorylation loop amplifies lactate-driven cancer progressionBingsong Huang, Mingpeng Jin, Gaofeng Cui, et al.Nature Chemical Biology|April 14, 2025
Temporal oscillation of phospholipids promotes metabolic efficiencySen Yang, Yuan Wang, Sisi Huang, et al.Nature Chemical Biology|April 17, 2025
Induced proximity to PML protects TDP-43 from aggregation via SUMO-ubiquitin networksKristina Wagner, Jan Keiten-Schmitz, Bikash Adhikari, et al.Nature Chemical Biology|April 17, 2025
Galectin-13 reduces membrane localization of SLC7A11 for ferroptosis propagationHai-Liang Zhang, Yi-Qing Guo, Shan Liu, et al.Nature Chemical Biology|April 18, 2025
Plug-and-play engineering of modular polyketide synthasesZilei Huang, Shengling Xie, Run-Zhou Liu, et al.Pageof 293