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Nature Chemical Biology|April 2, 2025
TOPO-seq reveals DNA topology-induced off-target activity by Cas9 and base editorsMin Duan, Pan Gao, Yi-Zhou Zhang, et al.Nature Chemical Biology|April 4, 2025
Native top-down proteomics enables discovery in endocrine-resistant breast cancerFabio P Gomes, Kenneth R Durbin, Kevin Schauer, et al.Nature Chemical Biology|April 28, 2025
Monitoring in real time and far-red imaging of H2O2 dynamics with subcellular resolutionJustin Daho Lee, Amanda Nguyen, Chelsea E Gibbs, et al.Nature Chemical Biology|March 29, 2025
Post-transcriptional modular synthetic receptorsXiaowei Zhang, Luis S Mille-Fragoso, K Eerik Kaseniit, et al.Nature Chemical Biology|May 28, 2025
Reactivity-based metabolomics reveal cysteine has glyoxalase 1-like and glyoxalase 2-like activitiesMarc Daniel Opfermann, Maria Bøgelund Søndergård, Louise Vase Bech, et al.Nature Chemical Biology|May 26, 2025
Eukaryotic ADCY7 catalyzes the production of c-di-AMP to activate the NLRP3 inflammasomeQiannv Liu, Zhiheng Tang, Yan Qian, et al.Nature Chemical Biology|May 26, 2025
Acetylation profiling by Iseq-Kac reveals insights into HSC aging and lineage decisionYanqiu Gong, Huiwen Zhan, Ni Wei, et al.Nature Chemical Biology|June 19, 2025
Click biology highlights the opportunities from reliable biological reactionsMark R HowarthNature Chemical Biology|February 13, 2026
Adhesion GPCR-induced ectocytosis mediates intercellular GPCR signal propagationGuobing Huang, Ni Li, Yiyang Chen, et al.Nature Chemical Biology|February 3, 2026
Inhibitory probes for spatiotemporal analysis of Gαs protein signalingJingyi Zhao, Alex Luebbers, Sofya Savransky, et al.Pageof 293