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Nature Medicine|February 3, 2026
High-dose nusinersen for spinal muscular atrophy: a phase 3 randomized trialRichard S Finkel, Thomas O Crawford, Eugenio Mercuri, et al.Nature Medicine|January 27, 2026
Humoral IgG1 responses to tumor antigens underpin clinical outcomes in immune checkpoint blockadeEdgar Gonzalez-Kozlova, Robert Sweeney, Igor Figueiredo, et al.Nature Medicine|January 28, 2026
Fecal microbiota transplantation plus pembrolizumab and axitinib in metastatic renal cell carcinoma: the randomized phase 2 TACITO trialSerena Porcari, Chiara Ciccarese, Vitor Heidrich, et al.Nature Medicine|January 28, 2026
Fecal microbiota transplantation plus immunotherapy in metastatic renal cell carcinoma: the phase 1 PERFORM trialRicardo Fernandes, Behnam Jabbarizadeh, Adnan Rajeh, et al.Nature Medicine|January 20, 2026
Holistic evaluation of large language models for medical tasks with MedHELMSuhana Bedi, Hejie Cui, Miguel Fuentes, et al.Nature Medicine|January 21, 2026
Clinical genetic variation across Hispanic populations in the Mexican BiobankCarmina Barberena-Jonas, Santiago G Medina-Muñoz, Viankail Cedillo-Castelán, et al.Nature Medicine|January 16, 2026
Single-cell atlas of the developing Down syndrome brain cortexMichael Lattke, Wee Leng Tan, Salil Kalarikkal Sukumaran, et al.Nature Medicine|January 16, 2026
External trigeminal nerve stimulation in youth with ADHD: a randomized, sham-controlled, phase 2b trialAldo Alberto Conti, Natali Bozhilova, Irem Ece Eraydin, et al.Nature Medicine|January 6, 2026
Real-world clinical utility of comprehensive genomic profiling in advanced solid tumorsYuki Saito, Sara Horie, Yasunori Kogure, et al.Nature Medicine|January 7, 2026
CD19 CAR-T cells for treatment-refractory autoimmune diseases: the phase 1/2 CASTLE basket trialFabian Müller, Melanie Hagen, Andreas Wirsching, et al.Pageof 624