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Nature Methods|September 5, 2026
Large-scale single-molecule analysis of tau proteoformsJames Joly, Vivekananda Budamagunta, Zhengjian Zhang, et al.Nature Methods|July 30, 2026
Inference of secreted protein signaling activities in intercellular communicationBeibei Ru, Lanqi Gong, Emily Yang, et al.Nature Methods|August 24, 2026
Overcoming air-water interface-induced artifacts in cryo-EM with protein nanocratesMatthew C Jenkins, Daija Bobe, Jake D Johnston, et al.Nature Methods|September 9, 2026
Reconstructing signaling histories of single cells via perturbation screens and transfer learningNicholas T Hutchins, Miram Meziane, Claire Lu, et al.Nature Methods|September 12, 2026
An ultralow-background far-red light-responsive optogenetic tool based on an engineered biliverdin-binding domainGiang N T Le, Lam M T Pham, Boyan Xue, et al.Nature Methods|September 30, 2026
CytoVI: deep generative modeling of antibody-based single cell dataFlorian Ingelfinger, Nathan Levy, Can Ergen, et al.Nature Methods|October 14, 2026
LoL-align: sensitive and fast probabilistic protein structure alignmentLasse Reifenrath, Michel van Kempen, Gyuri Kim, et al.Nature Methods|September 24, 2026
ResolVI: addressing noise and bias in spatial transcriptomicsCan Ergen, Nir YosefNature Methods|September 25, 2026
Spatially resolved chromatin architectures in mammalian brain tissuesZhenping Chen, Maoni Guo, Lin Zhang, et al.Nature Methods|October 23, 2026
Benchmarking segmentation methods for spatial transcriptomicsXabier Martínez-de-Morentin, Sumeer A Khan, Alberto Maillo, et al.Pageof 344