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Nature Methods|December 17, 2025
Orthogonal RNA-regulated destabilization domains for three-color RNA imaging with minimal RNA perturbationTien G Pham, Omoyemi Ajayi, Jiaze He, et al.Nature Methods|December 16, 2025
MultiCell: geometric learning in multicellular developmentHaiqian Yang, George Roy, Anh Q Nguyen, et al.Nature Methods|December 13, 2025
Bio-friendly and high-precision super-resolution imaging through self-supervised reconstruction structured illumination microscopyJiahao Liu, Xue Dong, Huaide Lu, et al.Nature Methods|December 10, 2025
Novae: a graph-based foundation model for spatial transcriptomics dataQuentin Blampey, Hakim Benkirane, Nadège Bercovici, et al.Nature Methods|December 10, 2025
Systematic evaluation of computational tools for multitype RNA modification detection using nanopore direct RNA sequencingTingting Luo, Moping Xu, Miao Wang, et al.Nature Methods|December 4, 2025
Latent space-based network analysis for brain-behavior linking in neuroimagingSelena Wang, Xinzhi Zhang, Yunhe Liu, et al.Nature Methods|December 2, 2025
Parallel stopped-flow interrogation of diverse biological systems at the single-molecule scaleRoman Kiselev, Ryan A Brady, Arnab Modak, et al.Nature Methods|December 1, 2025
Multimodal foundation transformer models for multiscale genomicsSumeer Ahmad Khan, Xabier Martínez-de-Morentin, Abdel Rahman Alsabbagh, et al.Nature Methods|December 23, 2024
Elucidating subcellular architecture and dynamics at isotropic 100-nm resolution with 4Pi-SIMZijing Ouyang, Qian Wang, Xiaoyu Li, et al.Nature Methods|December 13, 2024
iFlpMosaics enable the multispectral barcoding and high-throughput comparative analysis of mutant and wild-type cellsIrene Garcia-Gonzalez, Stefano Gambera, Susana F Rocha, et al.Pageof 339