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Nature Structural & Molecular Biology|November 10, 2025
Hydrophilic metformin and hydrophobic biguanides inhibit mitochondrial complex I by distinct mechanismsZhaoxiang He, Fei Teng, Yanqing Yang, et al.Nature Structural & Molecular Biology|November 11, 2025
AlphaSync is an enhanced AlphaFold structure database synchronized with UniProtBenjamin Lang, Bálint Mészáros, Besian I Sejdiu, et al.Nature Structural & Molecular Biology|November 1, 2025
Mechanisms of DNMT3A-3L-mediated de novo DNA methylation on chromatinYan Yan, X Edward Zhou, Stacey L Thomas, et al.Nature Structural & Molecular Biology|November 3, 2025
Phosphorylation-dependent tuning of mRNA deadenylation ratesJames A W Stowell, Conny W H Yu, Zhuo A Chen, et al.Nature Structural & Molecular Biology|November 3, 2025
Mechanistic basis for protein conjugation in a diverged bacterial ubiquitination pathwayQiaozhen Ye, Minheng Gong, Jiaxi Cai, et al.Nature Structural & Molecular Biology|November 4, 2025
DICER1 hotspot mutation induces 3p microRNA gain of function via Argonaute strand switchSharan Malagobadan, Chunmei Shi, Acong Yang, et al.Nature Structural & Molecular Biology|July 16, 2025
Structural basis of ClC-3 transporter inhibition by TMEM9 and PtdIns(3,5)P2Marina Schrecker, Yeeun Son, Rosa Planells-Cases, et al.Nature Structural & Molecular Biology|June 25, 2025
The PURB-HOTAIR complex regulates p53-dependent promoter-specific transcriptional activationZhangchuan Xia, Ning Kon, Zhenyi Su, et al.Nature Structural & Molecular Biology|July 3, 2025
SNARE disassembly requires Sec18/NSF side loadingYousuf A Khan, K Ian White, Richard A Pfuetzner, et al.Nature Structural & Molecular Biology|June 30, 2025
Mechanisms for licensing origins of DNA replication in eukaryotic cellsBruce Stillman, John F X Diffley, Janet H IwasaPageof 366