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Pharmacology Research & Perspectives|August 15, 2017
Anticonvulsive evaluation of THIP in the murine pentylenetetrazole kindling model: lack of anticonvulsive effect of THIP despite functional δ-subunit-containing GABAA receptors in dentate gyrus granule cellsCharlotte Simonsen, Kim Boddum, Nadia L von Schoubye, et al.Pharmacology Research & Perspectives|August 15, 2017
Experimental and clinical evidence of differential effects of magnesium sulfate on neuroprotection and angiogenesis in the fetal brainMatthieu Lecuyer, Marina Rubio, Clément Chollat, et al.Pharmacology Research & Perspectives|August 15, 2017
Ethics of animal research in human disease remediation, its institutional teaching; and alternatives to animal experimentationRajkumar Cheluvappa, Paul Scowen, Rajaraman EriPharmacology Research & Perspectives|August 15, 2017
Noncompetitive inhibition of human CYP2C9 in vitro by a commercial Rhodiola rosea productOle Kristian Forstrønen Thu, Olav Spigset, Bent HellumPharmacology Research & Perspectives|October 4, 2017
Lack of clinically important PK interaction between coformulated ledipasvir/sofosbuvir and rilpivirine/emtricitabine/tenofovir alafenamideJoseph M Custodio, Susan K Chuck, Hoa Chu, et al.Pharmacology Research & Perspectives|October 4, 2017
Mechanistic in vitro studies confirm that inhibition of the renal apical efflux transporter multidrug and toxin extrusion (MATE) 1, and not altered absorption, underlies the increased metformin exposure observed in clinical interactions with cimetidine, trimethoprim or pyrimethamineRobert Elsby, Stephen Chidlaw, Samuel Outteridge, et al.Pharmacology Research & Perspectives|October 4, 2017
Arginine-rich membrane-permeable peptides are seriously toxicQian Li, Mengchuan Xu, Yali Cui, et al.Pharmacology Research & Perspectives|October 4, 2017
Possible use of a H3R antagonist for the management of nonmotor symptoms in the Q175 mouse model of Huntington's diseaseDaniel S Whittaker, Huei-Bin Wang, Dawn H Loh, et al.Pharmacology Research & Perspectives|October 31, 2015
Inhibition of hERG potassium channel by the antiarrhythmic agent mexiletine and its metabolite m-hydroxymexiletineRoberta Gualdani, Francesco Tadini-Buoninsegni, Mariagrazia Roselli, et al.Pharmacology Research & Perspectives|October 31, 2015
Applicability of second-generation upcyte® human hepatocytes for use in CYP inhibition and induction studiesSarada D Ramachandran, Aurélie Vivarès, Sylvie Klieber, et al.Pageof 141