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RSC Medicinal Chemistry|August 18, 2025
Discovery of an orally bioavailable, CNS active pan-mutant RET kinase heterobifunctional degraderDouglas L Orsi, Kiel E Lazarski, Reina Improgo, et al.
RSC Medicinal Chemistry|August 7, 2025
Synthetic and structure-activity studies of SP2577 and TCP towards LSD1 targeting PROTACsMegan E Coulson, James K S Norris, Sean A Smith, et al.
RSC Medicinal Chemistry|September 15, 2025
Polyphenolic compounds as protective agents against cisplatin-induced ototoxicity with molecular mechanisms and clinical potentialTong Wei, Jing Nie, Dongbo Wang, et al.
RSC Medicinal Chemistry|September 8, 2025
Development of heterocyclic derivatives as P-glycoprotein inhibitors against multidrug resistance: pharmacological activities, structure-activity relationship and target (2020-2024)Zhikun Yang, Yanhong Yang, Zimeng Huang, et al.
RSC Medicinal Chemistry|September 8, 2025
Parallel synthesis of 5'-amino-5'-deoxy-adenosine derivatives for focused chemical space exploration and their application as methyltransferase inhibitorsSabrina N Hoba, Marvin Schwickert, Luis Kammerer, et al.
RSC Medicinal Chemistry|September 17, 2025
Development of a nitric oxide-releasing cephalexin-based hybrid compound for enhanced antimicrobial efficacy and biofilm disruptionSumit Kumar, Myddelton C Parker, Yi Wu, et al.
RSC Medicinal Chemistry|August 18, 2025
Polyethylene glycol incorporation to reduce the cytotoxicity associated with cationic cell-penetrating-peptide conjugationNaoki Umezawa, Kazuma Arakawa, Maiko Kato, et al.
RSC Medicinal Chemistry|August 18, 2025
Fragment-based discovery of dual ligand pharmacophores for lipid-sensing transcription factors for designed polypharmacologyTanja Stiller, Silke Duensing-Kropp, Julian A Marschner, et al.
RSC Medicinal Chemistry|September 8, 2025
Leveraging artificial intelligence and machine learning in kinase inhibitor development: advances, challenges, and future prospectsMohamed S Elgawish, Aya M Almatary, Sawsan A Zaitone, et al.
RSC Medicinal Chemistry|September 11, 2025
Bicyclic temporin L peptide inhibitors targeting the SARS-CoV-2 main protease: design, synthesis, in vitro inhibition efficiency and molecular dynamics insightsMd Taimuzzaman Sharif, Md Omor Farque, Md Habibur Rahaman, et al.
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